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Author/Creator Funk, Christoph

1. A double-tracer technique to characterize absorption, distribution, metabolism and excretion (ADME) of [14C]-basimglurant and absolute bioavailability after oral administration and concomitant intravenous microdose administration of [13C6]-labeled basimglurant in humans. (1st February 2017)

Authors:
Guerini, Elena; Schadt, Simone; Greig, Gerard; Haas, Ruth; Husser, Christophe; Zell, Manfred; Funk, Christoph; Hartung, Thomas; Gloge, Andreas; Mallalieu, Navita L.
Journal:
Xenobiotica
Issue:
Volume 47:Number 2(2017)
Page Start:
144
Record Type:
Journal Article
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2. Application of Imaging Techniques to Cases of Drug-Induced Crystal Nephropathy in Preclinical Studies. (27th February 2017)

Authors:
Lenz, Barbara; Brink, Andreas; Siam, Monira; De Paepe, Anne; Bassett, Simon; Eichinger-Chapelon, Anne; Maliver, Pierre; Neff, Rachel; Niederhauser, Urs; Steinhuber, Bernd; Zurbach, Raphael; Singer, Thomas; Funk, Christoph; Schuler, Franz; Albassam, Mudher; Schadt, Simone
Journal:
Toxicological sciences
Issue:
Volume 163:Number 2(2018)
Page Start:
409
Record Type:
Journal Article
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3. Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective. Issue 5 (22nd October 2018)

Authors:
Kenna, J. Gerry; Taskar, Kunal S.; Battista, Christina; Bourdet, David L.; Brouwer, Kim L.R.; Brouwer, Kenneth R.; Dai, David; Funk, Christoph; Hafey, Michael J.; Lai, Yurong; Maher, Jonathan; Pak, Y. Anne; Pedersen, Jenny M.; Polli, Joseph W.; Rodrigues, A. David; Watkins, Paul B.; Yang, Kyunghe...
Journal:
Clinical pharmacology & therapeutics
Issue:
Volume 104:Issue 5(2018)
Page Start:
916
Record Type:
Journal Article
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7. In vitro profiling of the metabolism and drug–drug interaction of tofogliflozin, a potent and highly specific sodium-glucose co-transporter 2 inhibitor, using human liver microsomes, human hepatocytes, and recombinant human CYP. (28th October 2014)

Authors:
Yamane, Mizuki; Kawashima, Kosuke; Yamaguchi, Koji; Nagao, Shunsuke; Sato, Mika; Suzuki, Masayuki; Honda, Kiyofumi; Hagita, Hitoshi; Kuhlmann, Olaf; Poirier, Agnes; Fowler, Stephen; Funk, Christoph; Simon, Sandrine; Aso, Yoshinori; Ikeda, Sachiya; Ishigai, Masaki
Journal:
Xenobiotica
Issue:
Volume 45:Number 3(2015:Mar.)
Page Start:
230
Record Type:
Journal Article
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Available online (eLD content is only available in our Reading Rooms) ↗

8. In vitro profiling of the metabolism and drug–drug interaction of tofogliflozin, a potent and highly specific sodium-glucose co-transporter 2 inhibitor, using human liver microsomes, human hepatocytes, and recombinant human CYP. (March 2015)

Authors:
Yamane, Mizuki; Kawashima, Kosuke; Yamaguchi, Koji; Nagao, Shunsuke; Sato, Mika; Suzuki, Masayuki; Honda, Kiyofumi; Hagita, Hitoshi; Kuhlmann, Olaf; Poirier, Agnes; Fowler, Stephen; Funk, Christoph; Simon, Sandrine; Aso, Yoshinori; Ikeda, Sachiya; Ishigai, Masaki
Journal:
Xenobiotica
Issue:
Volume 45:Number 3(2015:Mar.)
Page Start:
230
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗