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Author/Creator Forman, Mark

1. [O2–09–01]: ACUTE ADMINISTRATION OF A BACE INHIBITOR IN HEALTHY HUMANS RESULTS IN A SIGNIFICANT REDUCTION OF Aβ OLIGOMERS IN CEREBROSPINAL FLUID. (1st July 2017)

Authors:
Kalinina, Juliya; Cheon, Kyeongmi; Stone, Julie; Kennedy, Matthew; Forman, Mark; Egan, Michael F.; Tanen, Michael R.; Winrow, Christopher J.; Savage, Mary J.
Journal:
Alzheimer's & dementia
Issue:
Volume 13:Supplement 7S(2017)Part 11
Page Start:
P574
Record Type:
Journal Article
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2. Multiple comorbid neuropathologies in the setting of Alzheimer's disease neuropathology and implications for drug development. Issue 1 (20th September 2016)

Authors:
Rabinovici, Gil D.; Carrillo, Maria C.; Forman, Mark; DeSanti, Susan; Miller, David S.; Kozauer, Nicholas; Petersen, Ronald C.; Randolph, Christopher; Knopman, David S.; Smith, Eric E.; Isaac, Maria; Mattsson, Niklas; Bain, Lisa J.; Hendrix, James A.; Sims, John R.
Journal:
Alzheimer's & dementia
Issue:
Volume 3:Issue 1(2017)
Page Start:
83
Record Type:
Journal Article
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3. O1–06–05: The novel BACE inhibitor MK‐8931 dramatically lowers CSF beta‐amyloid in patients with mild‐to‐moderate Alzheimer's disease. (1st July 2013)

Authors:
Forman, Mark; Kleijn, Huub‐Jan; Dockendorf, Marissa; Palcza, John; Tseng, Jack; Canales, Christina; Egan, Michael; Kennedy, Matthew; Laterza, Omar; Ma, Lei; Scott, Jack; Tanen, Michael; Apter, Jeffrey; Backonja, Miroslav; Ereshefsky, Larry; Gevorkyan, Hakop; Jhee, Stanford; Rynders, Rebecca; Zari...
Journal:
Alzheimer's & dementia
Issue:
Volume 9:Supplement 4S(2013)Part 3
Page Start:
P139
Record Type:
Journal Article
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4. O2‐13‐04: Early Clinical Results and Preclinical Validation of the O‐Glcnacase (OGA) Inhibitor Mk‐8719 as a Novel Therapeutic for the Treatment of Tauopathies. (1st July 2016)

Authors:
Smith, Sean M.; Struyk, Arie; Jonathan, Daniel; Declercq, Ruben; Marcus, Jacob; Toolan, Dawn; Wang, Xiaohai; Schachter, Joel B.; Cosden, Mali; Pearson, Michelle; Hess, Fred; Selnick, Harold; Salinas, Cristian; Li, Wenping; Duffy, Joseph; McEachern, Ernest; Vocadlo, David; Renger, John J.; Eric, H...
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Supplement 7S(2016)Part 5
Page Start:
P261
Record Type:
Journal Article
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5. O4–05–05: Consistency of BACE inhibitor‐mediated brain amyloid production inhibition by MK‐8931 in Alzheimer's disease patients and healthy young adults. (1st July 2013)

Authors:
Stone, Julie; Kleijn, Huub Jan; Dockendorf, Marissa; Ma, Lei; Palcza, John; Tseng, Jack; Tanen, Michael; Forman, Mark
Journal:
Alzheimer's & dementia
Issue:
Volume 9:Supplement 4S(2013)Part 17
Page Start:
P690
Record Type:
Journal Article
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7. P1–361: Improved interpretation of amyloid tracer kinetic data through model‐based analysis. (1st July 2013)

Authors:
Stone, Julie; Kleijn, Huub Jan; Bradstreet, Thomas E.; Drexel, Melissa; Savage, Mary; Forman, Mark; Spellman, Daniel; Laterza, Omar; Chappell, Derek; Chappell, Gloria; Tanen, Michael; Cumming, Jared; Hyde, Lynn; Kennedy, Matthew; Struyk, Arie
Journal:
Alzheimer's & dementia
Issue:
Volume 9:Supplement 4S(2013)Part 7
Page Start:
P290
Record Type:
Journal Article
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8. P213 - A priori prediction of CYP3A victim drug-drug interaction of MK-1 and diltiazem using physiologically-based pharmacokinetic modeling (PBPK): qualification using clinical data. (2020)

Authors:
Gibson, Christopher; Hartmann, Georgy; Ma, Bennett; Chain, Anne; Smith, Sean; Forman, Mark; Datta, Sandip; Bateman, Thomas; Li, Ying; Khalilieh, Sauzanne
Journal:
Drug metabolism and pharmacokinetics
Issue:
Volume 35(2020)Supplement 1
Page Start:
S87
Record Type:
Journal Article
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9. P2‐002: AN INTEGRATED MECHANISTIC AMYLOID PATHWAY MODEL INFORMED BY CLINICAL BIOMARKER DATA FROM VERUBECESTAT AND OTHER BACE INHIBITORS. (1st July 2019)

Authors:
Rasmussen, Christian; Kleijn, Huub Jan; Kalinina, Juliya; Dockendorf, Marissa; Savage, Mary J.; Struyk, Arie; Forman, Mark; Stone, Julie A.
Journal:
Alzheimer's & dementia
Issue:
Volume 15:Supplement 7(2019)Part 11
Page Start:
P571
Record Type:
Journal Article
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10. P2‐005: Evidence from Model‐Based Assessments of Compounds Tested in Completed Clinical Trials Indicates That The Amyloid Hypothesis Has Not Been Adequately Tested. (1st July 2016)

Authors:
Stone, Julie A.; Kleijn, Huub Jan; Dockendorf, Marissa; Mo, Yi; Egan, Michael; Forman, Mark
Journal:
Alzheimer's & dementia
Issue:
Volume 12:Supplement 7S(2016)Part 12
Page Start:
P609
Record Type:
Journal Article
View Content:
Available online (eLD content is only available in our Reading Rooms) ↗