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You searched for: Author/Creator Eis, Knut- Eis, Knut [remove] 5
- Pharmaceutical chemistry -- Periodicals 4
- 615.19005 3
- free-energy perturbation (FEP) -- KRAS -- medicinal chemistry -- molecular dynamics -- virtual library design 2
- 615.19 1
- 616.994 1
- ACN acetonitrile -- AUC0-tlast, norm AUC from time 0 to the last data point normalized by the dose administered -- CL total body clearance of drug from measured matrix -- Cmax maximum observed drug concentration -- Cmax, unb. maximum observed drug concentration corrected for plasma protein binding -- DCM dichloromethane -- DPPF 1, 1′-Bis(diphenylphosphino)ferrocene -- EtOH ethanol -- Emax maximal efficacy -- GSH glutathione -- HATU Hexafluorophosphate Azabenzotriazole Tetramethyl Uronium -- LBD ligand binding domain -- NCOR nuclear receptor corepressor -- PPAR peroxisome proliferator-activated receptor -- RP reverse phase -- RXR retinoid X receptor -- Tmax time to reach Cmax -- Vss volume of distribution at steady state 1
- AML acute myeloid leukemia -- ATP adenosine triphosphate -- BID twice daily -- CDK cyclin-dependent kinase -- DMSO dimethyl sulfoxide -- eIF4E eukaryotic translation initiation factor 4E -- EMT epithelial-mesenchymal-transition -- FBS fetal bovine serum -- IC50 half maximal inhibitory concentration -- IL interleukin -- i.p. intraperitoneal application -- i.v. intravenous application -- LPS lipopolysaccharide -- MAPK mitogen-activated protein kinase -- MCP-1 monocyte chemotactic protein 1 -- MMP matrix-metalloprotease -- MNK1 MAP kinase-interacting kinase 1 -- NSCLC non-small cell lung cancer -- p.o. per oral application -- QD once daily -- T/C treatment/control -- TNFα tumor necrosis factor α -- V tumor volumes -- Vss volume of distribution 1
- Biochemistry -- Periodicals 1
- Bioorganic chemistry -- Periodicals 1
- Cancer -- Periodicals 1