1. Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys. Issue 17 (1st September 2015) Authors: Fischer, Christian; Zultanski, Susan L.; Zhou, Hua; Methot, Joey L.; Shah, Sanjiv; Hayashi, Ikuo; Hughes, Bethany L.; Moxham, Christopher M.; Bays, Nathan W.; Smotrov, Nadya; Hill, Armetta D.; Pan, Bo-Sheng; Wu, Zhenhua; Moy, Lily Y.; Tanga, Flobert; Kenific, Candia; Cruz, Jonathan C.; Walker, De... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 17(2015) Page Start: 3488 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Potent benzoazepinone γ-secretase modulators with improved bioavailability. Issue 17 (1st September 2015) Authors: Methot, Joey L.; Fischer, Christian; Li, Chaomin; Rivkin, Alexey; Ahearn, Sean P.; Brown, William Colby; Kattar, Sam; Kelley, Elizabeth; Mampreian, Dawn M.; Schell, Adam; Rosenau, Andrew; Zhou, Hua; Ball, Richard; Deshmukh, Sujal V.; Jeliazkova-Mecheva, Valentina V.; Diaz, Damaris; Moy, Lily Y.; ... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 17(2015) Page Start: 3495 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors. Issue 7 (1st April 2016) Authors: Simov, Vladimir; Deshmukh, Sujal V.; Dinsmore, Christopher J.; Elwood, Fiona; Fernandez, Rafael B.; Garcia, Yudith; Gibeau, Craig; Gunaydin, Hakan; Jung, Joon; Katz, Jason D.; Kraybill, Brian; Lapointe, Blair; Patel, Sangita B.; Siu, Tony; Su, Hua; Young, Jonathan R. Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 7(2016) Page Start: 1803 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗