Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys. Issue 17 (1st September 2015)

• Record Type: Journal Article
• Authors: Fischer, Christian; Zultanski, Susan L.; Zhou, Hua; Methot, Joey L.; Shah, Sanjiv; Hayashi, Ikuo; Hughes, Bethany L.; Moxham, Christopher M.; Bays, Nathan W.; Smotrov, Nadya; Hill, Armetta D.; Pan, Bo-Sheng; Wu, Zhenhua; Moy, Lily Y.; Tanga, Flobert; Kenific, Candia; Cruz, Jonathan C.; Walker, Deborah; Bouthillette, Melanie; Nikov, George N.; Deshmukh, Sujal V.; Jeliazkova-Mecheva, Valentina V.; Diaz, Damaris; Michener, Maria S.; Cook, Jacquelynn J.; Munoz, Benito; Shearman, Mark S.
• Is Part Of: Bioorganic & medicinal chemistry letters. Volume 25:Issue 17(2015)
• Page Start: 3488
• Page End: 3494
• Publication Date: 2015-09-01
• Subjects: Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1016/j.bmcl.2015.07.003
• Languages: English
• ISSNs: 0960-894X

Abstract

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