1. Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications. (3rd July 2015) Authors: Ford, Kevin A.; Ryslik, Gregory; Sodhi, Jasleen; Halladay, Jason; Diaz, Dolo; Dambach, Donna; Masuda, Melisa Journal: Drug metabolism reviews Issue: Volume 47:Number 3(2015:Jul.) Page Start: 291 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability. Issue 2 (15th January 2016) Authors: Young, Wendy B.; Barbosa, James; Blomgren, Peter; Bremer, Meire C.; Crawford, James J.; Dambach, Donna; Eigenbrot, Charles; Gallion, Steve; Johnson, Adam R.; Kropf, Jeffrey E.; Lee, Seung H.; Liu, Lichuan; Lubach, Joseph W.; Macaluso, Jen; Maciejewski, Pat; Mitchell, Scott A.; Ortwine, Daniel F.;... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 26:Issue 2(2016) Page Start: 575 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Integrated risk assessment of suicidal ideation and behavior in drug development. Issue 9 (September 2015) Authors: Muller, Patrick Y.; Dambach, Donna; Gemzik, Brian; Hartmann, Andreas; Ratcliffe, Sian; Trendelenburg, Christian; Urban, Laszlo Journal: Drug discovery today Issue: Volume 20:Issue 9(2015) Page Start: 1135 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. MEK and ERK Kinase Inhibitors Increase Circulating Ceruloplasmin and Cause Green Serum in Rats. (February 2017) Authors: Diaz, Dolores; Pai, Rama; Cain, Gary; La, Nghi; Dambach, Donna; Schwartz, Jacob; Tarrant, Jacqueline M. Other Names: Aulbach Adam guest-editor.; Jordan Holly guest-editor.; Tarrant Jacqueline guest-editor. Journal: Toxicologic pathology Issue: Volume 45:Number 2(2017) Page Start: 353 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Mitigation of opioid off-target effects and identification of structural drivers of opioid receptor engagement for BACE-1 small molecule inhibitors. (24th July 2015) Authors: Diaz, Dolores; Dambach, Donna; Siu, Michael; Hunt, Kevin; Thomas, Allen; Lyssikatos, Joseph; Liu, Xingrong; Lewin-Koh, Sock; McCray, Bobby; Ford, Kevin Journal: Toxicology mechanisms and methods Issue: Volume 25:Number 6(2015) Page Start: 478 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Potent and selective Bruton's tyrosine kinase inhibitors: Discovery of GDC-0834. Issue 6 (15th March 2015) Authors: Young, Wendy B.; Barbosa, James; Blomgren, Peter; Bremer, Meire C.; Crawford, James J.; Dambach, Donna; Gallion, Steve; Hymowitz, Sarah G.; Kropf, Jeffrey E.; Lee, Seung H.; Liu, Lichuan; Lubach, Joseph W.; Macaluso, Jen; Maciejewski, Pat; Maurer, Brigitte; Mitchell, Scott A.; Ortwine, Daniel F.;... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 6(2015) Page Start: 1333 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Potent and selective Bruton's tyrosine kinase inhibitors: Discovery of GDC-0834. Issue 6 (15th March 2015) Authors: Young, Wendy B.; Barbosa, James; Blomgren, Peter; Bremer, Meire C.; Crawford, James J.; Dambach, Donna; Gallion, Steve; Hymowitz, Sarah G.; Kropf, Jeffrey E.; Lee, Seung H.; Liu, Lichuan; Lubach, Joseph W.; Macaluso, Jen; Maciejewski, Pat; Maurer, Brigitte; Mitchell, Scott A.; Ortwine, Daniel F.;... Journal: Bioorganic & medicinal chemistry letters Issue: Volume 25:Issue 6(2015) Page Start: 1333 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid. (20th April 2015) Authors: Tarrant, Jacqueline M.; Dhawan, Preeti; Singh, Jatinder; Zabka, Tanja S.; Clarke, Emer; DosSantos, Garry; Dragovich, Peter S.; Sampath, Deepak; Lin, Tori; McCray, Bobbi; La, Nghi; Nguyen, Trung; Kauss, Ariel; Dambach, Donna; Misner, Dinah L.; Diaz, Dolores; Uppal, Hirdesh Journal: Toxicology mechanisms and methods Issue: Volume 25:Number 3(2015) Page Start: 201 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗