1. A Phase 1, Placebo-controlled, Randomized, Single Ascending Dose Study and a Volunteer Infection Study to Characterize the Safety, Pharmacokinetics, and Antimalarial Activity of the Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048. (2nd April 2020) Authors: McCarthy, James S; Donini, Cristina; Chalon, Stephan; Woodford, John; Marquart, Louise; Collins, Katharine A; Rozenberg, Felix D; Fidock, David A; Cherkaoui-Rbati, Mohammed H; Gobeau, Nathalie; Möhrle, Jörg J Journal: Clinical infectious diseases Issue: Volume 71:Number 10(2020) Page Start: e657 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. A Randomized Trial Evaluating the Prophylactic Activity of DSM265 Against Preerythrocytic Plasmodium falciparum Infection During Controlled Human Malarial Infection by Mosquito Bites and Direct Venous Inoculation. (5th December 2017) Authors: Murphy, Sean C; Duke, Elizabeth R; Shipman, Kelly J; Jensen, Ryan L; Fong, Youyi; Ferguson, Sue; Janes, Holly E; Gillespie, Kevin; Seilie, Annette M; Hanron, Amelia E; Rinn, Laurie; Fishbaugher, Matthew; VonGoedert, Tracie; Fritzen, Emma; Kappe, Stefan H; Chang, Ming; Sousa, Jason C; Marcsisin, S... Journal: Journal of infectious diseases Issue: Volume 217:Number 5(2018) Page Start: 693 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. Antimalarial Activity of Artefenomel Against Asexual Parasites and Transmissible Gametocytes During Experimental Blood-Stage Plasmodium vivax Infection. (1st June 2020) Authors: Collins, Katharine A; Abd-Rahman, Azrin N; Marquart, Louise; Ballard, Emma; Gobeau, Nathalie; Griffin, Paul; Chalon, Stephan; Möhrle, Jörg J; McCarthy, James S Journal: Journal of infectious diseases Issue: Volume 225:Number 6(2022) Page Start: 1062 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Concentration‐QT modelling of the novel DHFR inhibitor P218 in healthy male volunteers. Issue 1 (9th July 2021) Authors: Täubel, Jӧrg; Lorch, Ulrike; Ferber, Georg; Spencer, Christopher S.; Freier, Anne; Coates, Simon; El Gaaloul, Myriam; Donini, Cristina; Chughlay, Mohamed Farouk; Chalon, Stephan Other Names: Magavern Emma guestEditor.; Piasecki Jan guestEditor.; Cremers Serge guestEditor.; Cohen Adam guestEditor. Journal: British journal of clinical pharmacology Issue: Volume 88:Issue 1(2022) Page Start: 128 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection. Issue 6 (June 2017) Authors: Sulyok, Mihály; Rückle, Thomas; Roth, Alexandra; Mürbeth, Raymund E; Chalon, Stephan; Kerr, Nicola; Samec, Sonia Schnieper; Gobeau, Nathalie; Calle, Carlos Lamsfus; Ibáñez, Javier; Sulyok, Zita; Held, Jana; Gebru, Tamirat; Granados, Patricia; Brückner, Sina; Nguetse, Christian; Mengue, Juliana; L... Journal: Lancet infectious diseases Issue: Volume 17:Issue 6(2017:Jun.) Page Start: 636 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Effect of moxidectin on CYP3A4 activity as evaluated by oral midazolam pharmacokinetics in healthy subjects. Issue 2 (22nd October 2013) Authors: Korth‐Bradley, Joan M.; Parks, Virginia; Wagner, Frank; Chalon, Stephan; Gourley, Ian; Matschke, Kyle; Gossart, Sophie; Ripp, Sharon L.; Fleckenstein, Lawrence Journal: Clinical pharmacology in drug development Issue: Volume 3:Issue 2(2014:Mar./Apr.) Page Start: 151 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. First‐in‐human clinical trial to assess the safety, tolerability and pharmacokinetics of P218, a novel candidate for malaria chemoprotection. Issue 6 (12th February 2020) Authors: Chughlay, M. Farouk; Rossignol, Emilie; Donini, Cristina; El Gaaloul, Myriam; Lorch, Ulrike; Coates, Simon; Langdon, Grant; Hammond, Tim; Möhrle, Jörg; Chalon, Stephan Journal: British journal of clinical pharmacology Issue: Volume 86:Issue 6(2020) Page Start: 1113 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium vivax Volunteer Infection Study. Issue 5 (2nd July 2020) Authors: Abd‐Rahman, Azrin N.; Marquart, Louise; Gobeau, Nathalie; Kümmel, Anne; Simpson, Julie A.; Chalon, Stephan; Möhrle, Jörg J.; McCarthy, James S. Journal: Clinical pharmacology & therapeutics Issue: Volume 108:Issue 5(2020) Page Start: 1055 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Posttreatment Transaminase Elevations in Controlled Human Malaria Infection and Naturally Acquired Malaria. (5th October 2021) Authors: Odedra, Anand; Woodford, John; Chalon, Stephan; Barber, Bridget E; McCarthy, James S Journal: Journal of infectious diseases Issue: Volume 225:Number 5(2022) Page Start: 926 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study. Issue 6 (June 2022) Authors: Barber, Bridget E; Fernandez, Melissa; Patel, Hardik Babubhai; Barcelo, Catalina; Woolley, Stephen D; Patel, Harilal; Llewellyn, Stacey; Abd-Rahman, Azrin N; Sharma, Sunil; Jain, Mukul; Ghoghari, Ashok; Di Resta, Ilaria; Fuchs, Aline; Deni, Ioanna; Yeo, Tomas; Mok, Sachel; Fidock, David A; Chalon... Journal: Lancet infectious diseases Issue: Volume 22:Issue 6(2022) Page Start: 879 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗