1. Current nonclinical approaches for immune assessments of immuno-oncology biotherapeutics. Issue 2 (February 2023) Authors: Grimaldi, Christine; Ibraghimov, Alex; Kiessling, Andrea; Rattel, Benno; Ji, Changhua; Fuller, Claudette L.; Brennan, Frank R.; Regenass-Lechner, Franziska; Shenton, Jacintha; Price, Karen D.; Piché, Marie-Soleil; Steeves, Meredith A.; Prell, Rodney; Dudal, Sherri; Kronenberg, Sven; Freebern, Wen... Journal: Drug discovery today Issue: Volume 28:Issue 2(2023) Page Start: Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration. Issue 7 (3rd October 2018) Authors: Smith, Bryan; Kiessling, Andrea; Lledo-Garcia, Rocio; Dixon, Kate L.; Christodoulou, Louis; Catley, Matthew C.; Atherfold, Paul; D'Hooghe, Lena E.; Finney, Helene; Greenslade, Kevin; Hailu, Hanna; Kevorkian, Lara; Lightwood, Daniel; Meier, Christoph; Munro, Rebecca; Qureshi, Omar; Sarkar, Kaushik... Journal: MAbs Issue: Volume 10:Issue 7(2018) Page Start: 1111 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. In vitro assays supporting the safety assessment of immunomodulatory monoclonal antibodies. (December 2017) Authors: Brennan, Frank R.; Kiessling, Andrea Journal: Toxicology in vitro Issue: Volume 45:Part 3(2017) Page Start: 296 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. Integration of Consortia Recommendations for Justification of Animal Use Within Current and Future Drug Development Paradigms. (July 2019) Authors: Prior, Helen; Monticello, Thomas; Boulifard, Virginie; Brennan, Frank R.; Kimber, Ian Journal: International journal of toxicology Issue: Volume 38:Number 4(2019) Page Start: 319 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Optimized Nonclinical Safety Assessment Strategies Supporting Clinical Development of Therapeutic Monoclonal Antibodies Targeting Inflammatory Diseases. Issue 3 (29th April 2014) Authors: Brennan, Frank R.; Cauvin, Annick; Tibbitts, Jay; Wolfreys, Alison Journal: Drug development research Issue: Volume 75:Issue 3(2014) Page Start: 115 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Safety testing of monoclonal antibodies in non-human primates: Case studies highlighting their impact on human risk assessment. Issue 1 (2nd January 2018) Authors: Brennan, Frank R.; Cavagnaro, Joy; McKeever, Kathleen; Ryan, Patricia C.; Schutten, Melissa M.; Vahle, John; Weinbauer, Gerhard F.; Marrer-Berger, Estelle; Black, Lauren E. Journal: MAbs Issue: Volume 10:Issue 1(2018) Page Start: 1 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Strategies and Recommendations for Using a Data‐Driven and Risk‐Based Approach in the Selection of First‐in‐Human Starting Dose: An International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Assessment. Issue 6 (3rd November 2020) Authors: Leach, Michael W.; Clarke, David O.; Dudal, Sherri; Han, Chao; Li, Chunze; Yang, Zheng; Brennan, Frank R.; Bailey, Wendy J.; Chen, Yingxue; Deslandes, Antoine; Loberg, Lise I.; Mayawala, Kapil; Rogge, Mark C.; Todd, Marque; Chemuturi, Nagendra V. Journal: Clinical pharmacology & therapeutics Issue: Volume 109:Issue 6(2021) Page Start: 1395 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Translational immunotoxicology of immunomodulatory monoclonal antibodies. (September 2016) Authors: Brennan, Frank R.; Kiessling, Andrea Journal: Drug discovery today Issue: Volume 21/22(2016) Page Start: 85 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗