1. A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066. Issue 13 (1st July 2017) Authors: De Fusco, Claudia; Brear, Paul; Iegre, Jessica; Georgiou, Kathy Hadje; Sore, Hannah F.; Hyvönen, Marko; Spring, David R. Journal: Bioorganic & medicinal chemistry Issue: Volume 25:Issue 13(2017) Page Start: 3471 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
2. A fragment-based approach leading to the discovery of inhibitors of CK2α with a novel mechanism of action. Issue 11 (16th September 2022) Authors: Brear, Paul; De Fusco, Claudia; Atkinson, Eleanor L.; Iegre, Jessica; Francis-Newton, Nicola J.; Venkitaraman, Ashok R.; Hyvönen, Marko; Spring, David R. Journal: RSC medicinal chemistry Issue: Volume 13:Issue 11(2022) Page Start: 1420 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
3. A Random Forest Model for Predicting Allosteric and Functional Sites on Proteins. Issue 3 (21st January 2016) Authors: Chen, Ava S.‐Y.; Westwood, Nicholas J.; Brear, Paul; Rogers, Graeme W.; Mavridis, Lazaros; Mitchell, John B. O. Journal: Molecular informatics Issue: Volume 35:Issue 3/4(2016) Page Start: 125 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
4. ALDH2 Mediates 5-Nitrofuran Activity in Multiple Species. Issue 11 (19th November 2020) Authors: Zhou, Linna; Ishizaki, Hironori; Spitzer, Michaela; Taylor, Kerrie L.; Temperley, Nicholas D.; Johnson, Stephen L.; Brear, Paul; Gautier, Philippe; Zeng, Zhiqiang; Mitchell, Amy; Narayan, Vikram; McNeil, Ewan M.; Melton, David W.; Smith, Terry K.; Tyers, Mike; Westwood, Nicholas J.; Patton, E. El... Journal: Cell chemical biology Issue: Volume 27:Issue 11(2020) Page Start: 1452 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
5. Crystal structure of the Rho‐associated coiled‐coil kinase 2 inhibitor belumosudil bound to CK2α. Issue 10 (26th September 2022) Authors: Brear, Paul; Hyvönen, Marko Journal: Acta crystallographica Issue: Volume 78:Issue 10(2022) Page Start: 348 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
6. Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion. Issue 39 (21st May 2020) Authors: Kidd, Sarah L.; Fowler, Elaine; Reinhardt, Till; Compton, Thomas; Mateu, Natalia; Newman, Hector; Bellini, Dom; Talon, Romain; McLoughlin, Joseph; Krojer, Tobias; Aimon, Anthony; Bradley, Anthony; Fairhead, Michael; Brear, Paul; Díaz-Sáez, Laura; McAuley, Katherine; Sore, Hannah F.; Madin, Andrew... Journal: Chemical science Issue: Volume 11:Issue 39(2020) Page Start: 10792 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
7. Development of small cyclic peptides targeting the CK2α/β interface. Issue 30 (28th March 2022) Authors: Atkinson, Eleanor L.; Iegre, Jessica; D'Amore, Claudio; Brear, Paul; Salvi, Mauro; Hyvönen, Marko; Spring, David R. Journal: Chemical communications Issue: Volume 58:Issue 30(2022) Page Start: 4791 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
8. Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction. Issue 19 (18th April 2019) Authors: Iegre, Jessica; Brear, Paul; Baker, David J.; Tan, Yaw Sing; Atkinson, Eleanor L.; Sore, Hannah F.; O' Donovan, Daniel H.; Verma, Chandra S.; Hyvönen, Marko; Spring, David R. Journal: Chemical science Issue: Volume 10:Issue 19(2019) Page Start: 5056 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
9. Novel non-ATP competitive small molecules targeting the CK2 α/β interface. Issue 11 (15th July 2018) Authors: Brear, Paul; North, Andrew; Iegre, Jessica; Hadje Georgiou, Kathy; Lubin, Alexandra; Carro, Laura; Green, William; Sore, Hannah F.; Hyvönen, Marko; Spring, David R. Journal: Bioorganic & medicinal chemistry Issue: Volume 26:Issue 11(2018) Page Start: 3016 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗
10. Second-generation CK2α inhibitors targeting the αD pocket. Issue 11 (27th February 2018) Authors: Iegre, Jessica; Brear, Paul; De Fusco, Claudia; Yoshida, Masao; Mitchell, Sophie L.; Rossmann, Maxim; Carro, Laura; Sore, Hannah F.; Hyvönen, Marko; Spring, David R. Journal: Chemical science Issue: Volume 9:Issue 11(2018) Page Start: 3041 Record Type: Journal Article View Content: Available online (eLD content is only available in our Reading Rooms) ↗