Impact of COVID-19 on medical treatment patterns in gynecologic oncology: a MITO group survey. Issue 10 (23rd August 2021)

• Record Type: Journal Article
• Authors: Cioffi, Raffaella; Sabetta, Giulia; Rabaiotti, Emanuela; Bergamini, Alice; Bocciolone, Luca; Candotti, Giorgio; Candiani, Massimo; Valabrega, Giorgio; Mangili, Giorgia; Pignata, Sandro
• Other Names: author non-byline.; Sambataro Daniela author non-byline.; Mammoliti Serafina author non-byline.; Breda Enrico author non-byline.; D'Alessio Antonietta author non-byline.; Rondello Giacomo author non-byline.; Arcangeli Valentina author non-byline.; Messina Carlo author non-byline.; Artioli Grazia author non-byline.; Maneschi Francesco author non-byline.; Andreetta Claudia author non-byline.; Raspagliesi Francesco author non-byline.; Stefano Aida Di author non-byline.; Ditto Antonino author non-byline.; Garassino Isabella Maria Giovanna author non-byline.; Carella Claudia author non-byline.; Ferrandina Maria Gabriella author non-byline.; Narducci Filomena author non-byline.; Cirigliano Giovanna author non-byline.; Corrado Giacomo author non-byline.; Borghesi Simona author non-byline.; Legge Francesco author non-byline.; Bartoletti Michele author non-byline.; Giorgi Ugo De author non-byline.; Festi Anna author non-byline.; Ronzino Graziana author non-byline.; Scandurra Giusy author non-byline.; Kardhashi Anila author non-byline.; Zamagni Claudio author non-byline.; Petrella Maria Cristina author non-byline.; Mosconi Anna Maria author non-byline.; Pinto Giancarlo Di author non-byline.; Savarese Antonella author non-byline.; Perin Alessandra author non-byline.; Palma Teresa Di author non-byline.; Rubino Daniela author non-byline.; Zanaboni Flavia author non-byline.; Vertechy Laura author non-byline.; Roccio Marianna author non-byline.; Palaia Innocenza author non-byline.; Giovannoni Sara author non-byline.; Cassani Chiara author non-byline.; Sergi Domenico author non-byline.; Scotto Giulia author non-byline.; Lauria Rossella author non-byline.; Perrone Anna Myriam author non-byline.; Danese Saverio author non-byline.; Scarfone Giovanna author non-byline.;
• Is Part Of: International journal of gynecological cancer. Volume 31:Issue 10(2021)
• Page Start: 1363
• Page End: 1368
• Publication Date: 2021-08-23
• Subjects: COVID-19 -- ovarian cancer -- medical oncology; Generative organs, Female -- Cancer -- Periodicals; 616.99465
• DOI: 10.1136/ijgc-2021-002784
• Languages: English
• ISSNs: 1048-891X

Abstract

Abstract : Objective: COVID-19 is a global public health emergency. The increasing spread of COVID-19 presents challenges for the clinical care of patients with gynecological tumors. The Multicenter Italian Trials in Ovarian cancer and gynecologic malignancies (MITO) performed a survey to evaluate the impact of the COVID-19 pandemic on medical treatment of gynecological cancer, with a focus on chemotherapy and oral treatment with poly(ADP)-ribose polymerase inhibitors (PARP-i). Methods: The survey consisted of a self-administered online questionnaire, sent via email between November 2020 and January 2021 to all members of MITO group. Results: Forty-nine centers completed the questionnaire. The majority of respondents (83%) use screening tests to determine COVID-19 status in patients who were to undergo chemotherapy or oral medications. All respondents to our survey continued cancer therapy in patients who tested negative for COVID-19 during the pandemic. Seventy-three percent of respondents declared they stopped treatment with chemotherapy or PARP-i only after a positive swab and resumed therapy when negative tests were confirmed. Conclusions: COVID-19 positivity impacted patterns of treatment in patients diagnosed with ovarian cancer within the MITO group. Further investigations are needed to evaluate whether these modifications influence oncological clinical outcomes.