Advanced heart failure: from definitions to therapeutic options. (26th April 2023)

• Record Type: Journal Article
• Authors: Garascia, Andrea; Palazzini, Matteo; Tedeschi, Andrea; Sacco, Alice; Oliva, Fabrizio; Gentile, Piero
• Is Part Of: European heart journal supplements. Volume 25(2023)Supplement C
• Page Start: C283
• Page End: C291
• Publication Date: 2023-04-26
• Subjects: Advanced heart failure -- Heart transplantation -- Mechanical circulatory support; Cardiology -- Periodicals; Cardiology -- Europe -- Periodicals; 616.12005
• DOI: 10.1093/eurheartjsupp/suad028
• Languages: English
• ISSNs: 1520-765X

Abstract

Abstract: Advanced heart failure (AHF) represents an ominous stage of heart failure (HF), where the expected prognosis remains poor regardless of the improvement in medical knowledge. In this review, we summarize the definition, prognosis, physiopathology, and clinical/therapeutic management of the disease, focusing on the fast and timely referral of the patient to the AHF facilities. We provide an insight of the diagnostic and therapeutic 'work up' performed in an Italian AHF hub, implying a deep phenotypical patients characterization in order to evaluate candidacy to the therapeutic gold standards as heart transplantation (HTx) and left ventricular assist device (LVAD).