Bempedoic acid: what prospective uses?. (26th April 2023)

• Record Type: Journal Article
• Authors: Jacomelli, Ilaria; Monzo, Luca; Panattoni, Germana; Lanzillo, Chiara; Rebecchi, Marco; Calò, Leonardo
• Is Part Of: European heart journal supplements. Volume 25(2023)Supplement C
• Page Start: C109
• Page End: C111
• Publication Date: 2023-04-26
• Subjects: Bempedoic acid -- Cardiovascular disease -- LDL-cholesterol -- Statin intolerance; Cardiology -- Periodicals; Cardiology -- Europe -- Periodicals; 616.12005
• DOI: 10.1093/eurheartjsupp/suad012
• Languages: English
• ISSNs: 1520-765X

Abstract

Abstract: There is still the need to lower LDL-c, although the use of statins, ezetimibe and proprotein convertase subtilisin/kexin type 9. Patients with atherosclerotic cardiovascular disease and/or familial hypercholesterolaemia are treated with statins at maximum tolerated dose, with or without further lipid-lowering drugs, but very often, we can't reach the goal, so bempedoic acid treatment lead to a significant reduction in low-density lipoprotein cholesterol, in different groups of patients, with a favourable safety profile.