A case of bone lesion in a patient with relapsed chronic lymphocytic leukemia and review of the literature. Issue 4 (4th April 2022)

• Record Type: Journal Article
• Authors: Bacchiarri, Francesca; Gozzetti, Alessandro; Mondanelli, Nicola; Lazzi, Stefano; Bocchia, Monica
• Is Part Of: Clinical case reports. Volume 10:Issue 4(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-04-04
• Subjects: chronic lymphocytic leukemia -- hypercalcemia -- osteolysis; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.5379
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Skeletal involvement in CLL is very rare. We present a case of ileum bone lesion during in a patient receiving 5th line of therapy. Despite radiotherapy and salvage therapies, subsequent bone lesions led to a fatal outcome. Further studies on the mechanism by which bone disease develops are currently needed. Abstract : The mechanism by which bone lesions develop in CLL is unclear; further studies are needed in this regard, with the aim of developing more effective therapies. This case aims to review the literature, the modality of presentation and pathogenesis.