Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults. (21st June 2021)

• Record Type: Journal Article
• Authors: Zhuang, Zhenhuang; Gao, Meng; Lv, Jun; Yu, Canqing; Guo, Yu; Bian, Zheng; Yang, Ling; Du, Huaidong; Chen, Yiping; Ning, Feng; Liu, Huilin; Chen, Junshi; Chen, Zhengming; Huang, Tao; Li, Liming
• Other Names: Clarke Robert investigator.; Collins Rory investigator.; Peto Richard investigator.; Walters Robin investigator.; Avery Daniel investigator.; Boxall Ruth investigator.; Bennett Derrick investigator.; Chang Yumei investigator.; Gilbert Simon investigator.; Hacker Alex investigator.; Hill Mike investigator.; Holmes Michael investigator.; Iona Andri investigator.; Kartsonaki Christiana investigator.; Kerosi Rene investigator.; Kong Ling investigator.; Kurmi Om investigator.; Lancaster Garry investigator.; Lewington Sarah investigator.; Lin Kuang investigator.; McDonnell John investigator.; Millwood Iona investigator.; Nie Qunhua investigator.; Radhakrishnan Jayakrishnan investigator.; Ryder Paul investigator.; Sansome Sam investigator.; Schmidt Dan investigator.; Sherliker Paul investigator.; Sohoni Rajani investigator.; Stevens Becky investigator.; Turnbull Iain investigator.; Wang Jenny investigator.; Wang Lin investigator.; Wright Neil investigator.; Yang Xiaoming investigator.; Han Xiao investigator.; Hou Can investigator.; Pei Pei investigator.; Liu Chao investigator.; Tan Yunlong investigator.; Yu Canqing investigator.; Pang Zengchang investigator.; Gao Ruqin investigator.; Li Shanpeng investigator.; Wang Shaojie investigator.; Liu Yongmei investigator.; Du Ranran investigator.; Zang Yajing investigator.; Cheng Liang investigator.; Tian Xiaocao investigator.; Zhang Hua investigator.; Zhai Yaoming investigator.; Sun Xiaohui investigator.; Li Feifei investigator.; Lv Silu investigator.; Wang Junzheng investigator.; Hou Wei investigator.; Zeng Mingyuan investigator.; Jiang Ge investigator.; Zhou Xue investigator.; Yang Liqiu investigator.; He Hui investigator.; Yu Bo investigator.; Li Yanjie investigator.; Xu Qinai investigator.; Kang Quan investigator.; Guo Ziyan investigator.; Wang Dan investigator.; Hu Ximin investigator.; Chen Jinyan investigator.; Fu Yan investigator.; Fu Zhenwang investigator.; Wang Xiaohuan investigator.; Weng Min investigator.; Guo Zhendong investigator.; Wu Shukuan investigator.; Li Yilei investigator.; Li Huimei investigator.; Fu Zhifang investigator.; Wu Ming investigator.; Zhou Yonglin investigator.; Zhou Jinyi investigator.; Tao Ran investigator.; Yang Jie investigator.; Su Jian investigator.; liu Fang investigator.; Zhang Jun investigator.; Hu Yihe investigator.; Lu Yan investigator.; Ma Liangcai investigator.; Tang Aiyu investigator.; Zhang Shuo investigator.; Jin Jianrong investigator.; Liu Jingchao investigator.; Tang Zhenzhu investigator.; Chen Naying investigator.; Huang Ying investigator.; Li Mingqiang investigator.; Meng Jinhuai investigator.; Pan Rong investigator.; Jiang Qilian investigator.; Lan Jian investigator.; Liu Yun investigator.; Wei Liuping investigator.; Zhou Liyuan investigator.; Wang Ningyu Chen Ping investigator.; Meng Fanwen investigator.; Qin Yulu investigator.; Wang Sisi investigator.; Wu Xianping investigator.; Zhang Ningmei investigator.; Chen Xiaofang investigator.; Zhou Weiwei investigator.; Luo Guojin investigator.; Li Jianguo investigator.; Zhong Xunfu investigator.; Liu Jiaqiu investigator.; Sun Qiang investigator.; Ge Pengfei investigator.; Ren Xiaolan investigator.; Dong Caixia investigator.; Zhang Hui investigator.; Mao Enke investigator.; Wang Xiaoping investigator.; Wang Tao investigator.; zhang Xi investigator.; Zhang Ding investigator.; Zhou Gang investigator.; Feng Shixian investigator.; Fan Lei investigator.; Gao Yulian investigator.; He Tianyou investigator.; Sun Huarong investigator.; He Pan investigator.; Hu Chen investigator.; Zhang Xukui investigator.; Wu Huifang investigator.; Yu Min investigator.; Hu Ruying investigator.; Wang Hao investigator.; CDC Tongxiang investigator.; Qian Yijian investigator.; Wang Chunmei investigator.; Xie Kaixu investigator.; Chen Lingli investigator.; Zhang Yidan investigator.; Pan Dongxia investigator.; Gu Qijun investigator.; Huang Yuelong investigator.; Chen Biyun investigator.; Yin Li investigator.; Fu Zhongxi investigator.; Xu Qiaohua investigator.; Xu Xin investigator.; Zhang Hao investigator.; Long Huajun investigator.; Li Xianzhi investigator.; Zhang Libo investigator.; Qiu Zhe investigator.;
• Is Part Of: European journal of clinical investigation. Volume 51:Number 12(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-06-21
• Subjects: cardiovascular disease -- cohort study -- dental public health -- epidemiology -- oral hygiene; Pathology -- Periodicals; Medical research -- Periodicals; 616.075
• DOI: 10.1111/eci.13634
• Languages: English
• ISSNs: 0014-2972

Abstract

Abstract: Accumulating evidence has shown that poor oral hygiene is associated with increased risk of cardiometabolic diseases in Western populations. However, its relevance about the relationships in Chinese adults remains unclear. The China Kadoorie Biobank enrolled 512 715 adults aged 30‐79 years in China during 2004‐2008. Cox regression was used to estimate adjusted hazard ratios (HRs) for each disease associated with measures of oral hygiene. Overall 9.3% of the participants reported rarely or never brushing teeth at baseline. Participants who rarely or never brushed teeth had adjusted HR of 1.12 (95% CI: 1.09, 1.15) for MVE, with similar HRs for stroke (1.08, 1.05‐1.12), intracerebral haemorrhage (1.18, 1.11‐1.26) and pulmonary heart disease (1.22, 1.13‐1.32) compared with those who brushed teeth regularly. Those who did not brush teeth also had increased risk of cancer (1.09, 1.04‐1.14), chronic obstructive pulmonary disease (COPD) (1.12, 1.05‐1.20), liver cirrhosis (1.25, 1.09‐1.44) and all‐cause death (1.25, 1.21‐1.28) but not type 2 diabetes (0.94, 0.86‐1.03) and chronic kidney disease (0.98, 0.81‐1.18). Among Chinese adults, we found that poor oral hygiene is associated with higher risks of major vascular disease, cancer, COPD, liver cirrhosis and all‐cause deaths, but not type 2 diabetes and chronic kidney disease.