ZnS@BSA Nanoclusters Potentiate Efficacy of Cancer Immunotherapy (Adv. Mater. 49/2021). Issue 49 (7th December 2021)

• Record Type: Journal Article
• Authors: Cen, Dong; Ge, Qiwei; Xie, Congkun; Zheng, Qiang; Guo, Jiansheng; Zhang, Yuqi; Wang, Yifan; Li, Xiang; Gu, Zhen; Cai, Xiujun
• Is Part Of: Advanced materials. Volume 33:Issue 49(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-12-07
• Subjects: cancer immunotherapy -- cGAS/STING -- drug delivery -- hepatocellular carcinoma -- nanomedicine; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.202170390
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Cancer Therapy In article number 2104037, Xiang Li, Zhen Gu, Xiujun Cai, and co‐workers report that the generated H2 S and released zinc ions from ZnS@BSA nanoclusters promote accumulation of reactive oxygen species to activate cGAS/STING signals in tumor cells. ZnS@BSA nanoclusters are further demonstrated to facilitate antitumor immunotherapy by immune cell infiltration, showing potential for clinical translation.