Immune response during the onset of coliform mastitis in dairy cows vaccinated with STARTVAC®. (5th January 2021)

• Record Type: Journal Article
• Authors: Kawai, Kazuhiro; Kondo, Yasuha; Shinozuka, Yasunori; Kawata, Ryusaku; Kaneko, Sohei; Iwano, Hidetomo; Enokidani, Masafumi; Watanabe, Aiko; Yuliza‐Purba, Fika; Isobe, Naoki; Kurumisawa, Tomomi
• Is Part Of: Animal science journal. Volume 92:Number 1(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-01-05
• Subjects: bovine -- coliform mastitis -- early immune response -- host defense -- vaccination; Animal culture -- Periodicals; Livestock -- Periodicals; 636
• DOI: 10.1111/asj.13502
• Languages: English
• ISSNs: 1344-3941

Abstract

Abstract: The immune response during the onset of coliform mastitis in vaccinated cows was investigated by measuring lactoferrin (LF), interleukin‐8 ( IL‐8), and interleukin‐1β (IL‐1β) concentrations and somatic cell counts in 28 milk samples at the onset of acute coliform mastitis (ACM) and 73 milk samples at the onset of peracute coliform mastitis (PCM). Vaccinated ACM, unvaccinated ACM, and vaccinated PCM showed significantly higher values for LF and IL‐1β levels than unvaccinated PCM ( p < .01). The IL‐8 concentration was lower in vaccinated PCM than in unvaccinated PCM ( p < .05). There was no significant difference in somatic cell counts for each parameter. There were no significant differences in the parameters between vaccinated and unvaccinated ACM cows, or vaccinated ACM and PCM cows. From the above results, it is suggested that mastitis vaccination improved the early immune response, particularly at the onset of PCM, and played a large role in host defense against the initial infection.