Iodine‐Catalyzed Double [4+2] Oxidative Annulations for the Synthesis of Bipyrazines from Ketones and Diamines by a Domino Strategy. Issue 2 (13th October 2021)

• Record Type: Journal Article
• Authors: Ding, Yuxin; Zhang, Ruiqin; Ma, Renchao; Ma, Yongmin
• Is Part Of: Advanced synthesis & catalysis. Volume 364:Issue 2(2022)
• Page Start: 355
• Page End: 361
• Publication Date: 2021-10-13
• Subjects: Double annulation -- bipyrazine -- domino reaction -- iodine -- [4+2] cyclization; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202100991
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: An iodine‐catalyzed double [4+2] oxidative annulation of ketones and diamines is described. A multi‐pathway coupled domino strategy has been developed for the synthesis of substituted dimeric pyrazines under metal‐free conditions. One C−C and four C−N bonds are formed during this double [4+2] oxidative annulation process from two ketones and two diamines. Abstract :