Volumetric Bioprinting of Organoids and Optically Tuned Hydrogels to Build Liver‐Like Metabolic Biofactories (Adv. Mater. 15/2022). Issue 15 (14th April 2022)

• Record Type: Journal Article
• Authors: Bernal, Paulina Nuñez; Bouwmeester, Manon; Madrid‐Wolff, Jorge; Falandt, Marc; Florczak, Sammy; Rodriguez, Nuria Ginés; Li, Yang; Größbacher, Gabriel; Samsom, Roos‐Anne; van Wolferen, Monique; van der Laan, Luc J. W.; Delrot, Paul; Loterie, Damien; Malda, Jos; Moser, Christophe; Spee, Bart; Levato, Riccardo
• Is Part Of: Advanced materials. Volume 34:Issue 15(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-04-14
• Subjects: biofabrication -- bioresins -- hydrogels -- light‐based 3D printing -- volumetric additive manufacturing; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.202270112
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Volumetric Bioprinting Volumetric bioprinting shapes organoid‐laden constructs into centimeter‐scale assemblies that mimic native liver function. In article number 2110054, Riccardo Levato and co‐workers report the development of a hydrogel‐based bioresin with tunable optical properties to minimize scattering in light‐based printing and ensure high resolution. Organoid viability and maturation is preserved by the shear‐stress‐free printing, and salient liver functions mature in response to the 3D bioprinted architecture.