Heteroaromatic Hyperbranched Polyelectrolytes: Multicomponent Polyannulation and Photodynamic Biopatterning. (17th June 2021)

• Record Type: Journal Article
• Authors: Liu, Xiaolin; Xiao, Minghui; Xue, Ke; Li, Mingzhao; Liu, Dongming; Wang, Yong; Yang, Xinzhe; Hu, Yubing; Kwok, Ryan T. K.; Qin, Anjun; Zhu, Chunlei; Lam, Jacky W. Y.; Tang, Ben Zhong
• Is Part Of: Angewandte Chemie. Volume 133:Number 35(2021)
• Page Start: 19371
• Page End: 19380
• Publication Date: 2021-06-17
• Subjects: bacterial killing -- biopatterning -- multicomponent polymerization -- photodynamic therapy -- polyelectrolytes; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.202104709
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: We reported an efficient multicomponent polyannulation for in situ generation of heteroaromatic hyperbranched polyelectrolytes by using readily accessible internal diynes and low‐cost, commercially available arylnitriles, NaSbF6, and H2 O/AcOH. The polymers were obtained in excellent yields (up to 99 %) with extraordinary high molecular weights (Mw up to 1.011×10 6 ) and low polydispersity indices. The resulting polymers showed good processibility and high quantum yields with tunable emission in the solid state, making them ideal materials for highly ordered fluorescent photopatterning. These hyperbranched polyelectrolytes also possessed strong ability to generate reactive oxygen species, which allowed their applications in efficient bacterial killing and customizable photodynamic patterning of living organisms in a simple and cost‐effective way. Abstract : A multicomponent polymerization for the efficient synthesis of heteroaromatic hyperbranched polyelectrolytes was developed. These hyperbranched polymers showed excellent solubility, high quantum yields, tunable emission, and strong ROS generation ability, allowing for their widespread applications in highly ordered fluorescent photopatterning, efficient bacterial killing, and customizable photodynamic patterning of living organisms.