Topic: AS04-MDS Biology and Pathogenesis/AS04b-Clonal diversity & evolution: LONG-TERM MUTATIONAL DYNAMICS IN DEL(5Q) MDS PATIENTS EARLY TREATED WTIH LENALIDOMIDE (SINTRAREV CLINICAL TRIAL). SAFE AND EFFECITIVE APPROACH REGARDING CLONAL EVOLUTION?. (May 2023) - Castelló, S.M. Toribio; López-Cadenas, F.; Preudhomme, C.; Ramiro, A. Villaverde; Fenwarth, L.; Lumbreras, E.; Gonzalez, T.; Del Rey, M.; Xicoy, B.; Renneville, A.; Sánchez, J.; Coll, R.; et al.