Electrooxidative α-hydroxymethylation of ketones with dimethylformamide as the carbon source. Issue 8 (27th March 2023)

• Record Type: Journal Article
• Authors: Zheng, Jin-Ming; Li, Yi-Fei; Pan, Yi-Xiang; Hu, Xiao-Dong; Ye, Xiao-Xia; Li, Ren-Hao
• Is Part Of: Green chemistry. Volume 25:Issue 8(2023)
• Page Start: 3016
• Page End: 3020
• Publication Date: 2023-03-27
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/d3gc00144j
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : We report the electrocatalytic α-hydroxymethylation of ketones using DMF as the carbon source at room temperature in air in a conversion that proceeds without need for toxic and expensive chemical oxidants or metal catalysts. Abstract : An environmentally benign electrochemical approach has been developed for the α-hydroxymethylation of ketones using N, N -dimethylformamide as the carbon source for the construction of β-hydroxy ketones. This method does not require metal catalysts or chemical oxidants and proceeded smoothly at room temperature to demonstrate tolerance of a broad range of functional groups.