Motor point stimulation induces more robust F‐waves than peripheral nerve stimulation. (1st March 2022)

• Record Type: Journal Article
• Authors: Kaneko, Naotsugu; Fok, Kai Lon; Nakazawa, Kimitaka; Masani, Kei
• Is Part Of: European journal of neuroscience. Volume 55:Number 6(2022)
• Page Start: 1614
• Page End: 1628
• Publication Date: 2022-03-01
• Subjects: antidromic firing -- motoneuron excitability -- motor responses -- neuromuscular electrical stimulation; Nervous system -- Periodicals; 612.8
• DOI: 10.1111/ejn.15625
• Languages: English
• ISSNs: 0953-816X

Abstract

Abstract: The F‐wave is a motor response induced by electrical stimulation of peripheral nerves via the antidromic firing of motor nerves, which reflects the motoneuron excitability. To induce F‐waves, transcutaneous peripheral nerve stimulation (PNS) is used, which activates nerve branches via transcutaneous electrodes over the nerve branches. An alternative method to activate peripheral nerves, that is, motor point stimulation (MPS), which delivers electrical stimulation over the muscle belly, has not been used to induce F‐waves. In our previous studies, we observed that MPS induced F‐wave‐like responses, that is, motor responses at the latency of F‐waves at a supramaximal stimulation. Here, we further investigated the F‐wave‐like responses induced by MPS in comparison with PNS in the soleus muscle. Thirteen individuals participated in this study. We applied MPS and PNS on the participant's left soleus muscle. Using a monopolar double‐pulse stimulation, the amplitude of the second H‐reflex induced by PNS decreased, whereas the amplitude of the motor response at the F‐wave latency induced by MPS did not decrease. These results suggest that the motor response at the F‐wave latency induced by MPS was not an H‐reflex but an F‐wave. We also found that the F‐wave induced by MPS had a greater amplitude and higher persistence and caused less pain when compared with the F‐waves induced using PNS. We conclude that MPS evokes antidromic firing inducing F‐waves more consistently compared with PNS. Abstract : F‐waves reflect the spinal motoneuron excitability. Peripheral nerve stimulation (PNS) is used to induce F‐waves, whereas an alternative method to activate peripheral nerves, motor point stimulation (MPS), which delivers electrical stimulation over the muscle belly, has never been used. We showed that MPS induced F‐waves in the soleus muscle with higher persistence, larger amplitudes and less pain than ones induced using PNS.