Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats. (3rd May 2012)

• Record Type: Journal Article
• Authors: Lee, Liang-Ming; Lu, Chih-Cheng; Chung, Hsien-Hui; Cheng, Juei-Tang
• Other Names: Jann M. W. Academic Editor.; Komiya A. Academic Editor.; Naylor R. J. Academic Editor.
• Is Part Of: TheScientificWorldjournal. Volume 2012(2012)
• Publication Date: 2012-05-03
• Subjects: Science -- Periodicals; Technology -- Periodicals; Medicine -- Periodicals; 505
• DOI: 10.1100/2012/941685
• Languages: English
• ISSNs: 2356-6140

Abstract

Abstract : This paper shows a new finding about the decrease of relaxative response to loperamide in prostate of spontaneously hypertensive rats (SHR) as compare to normal rats (WKY). Authors demonstrated the reduction of ATP-sensitive potassium channels is resposible for this change using immunoblotting analysis and the decrease of action induced by diazoxide. This view is not mentioned before and is the first one reporting this result.