A Historical Review of the Total Synthesis of Natural Products Developed in Portugal. Issue 17 (25th March 2023)

• Record Type: Journal Article
• Authors: Clemente, Duarte B.; Coelho, Jaime A. S.
• Is Part Of: European journal of organic chemistry. Volume 26:Issue 17(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-03-25
• Subjects: alkaloids -- cyclitols -- natural products -- quinic acid -- total synthesis; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202300193
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: Total synthesis of natural products is an important discipline of organic chemistry that has enabled the development of new synthetic methods and strategies for the preparation and study of the structure and reactivity of complex naturally occurring products. In this review we summarize the synthetic strategies developed in Portugal by several research groups for the synthesis of bioactive natural products including alkaloids, cyclitols, fatty alcohols, phenylpropanoic acids, γ‐butyrolactones, xanthones and nucleosides. Abstract : This review summarizes the strategies for the natural product synthesis that were developed in Portugal in the past five decades, including alkaloids, cyclitols, phenylpropanoic acids, γ‐butyrolactones, fatty alcohols, xanthones and nucleosides.