Audiovisual integration in the human brain: a coordinate-based meta-analysis. (6th November 2022)

• Record Type: Journal Article
• Authors: Gao, Chuanji; Green, Jessica J; Yang, Xuan; Oh, Sewon; Kim, Jongwan; Shinkareva, Svetlana V
• Is Part Of: Cerebral cortex. Volume 33:Number 9(2023)
• Page Start: 5574
• Page End: 5584
• Publication Date: 2022-11-06
• Subjects: audiovisual integration -- fMRI -- PET -- meta-analysis; Cerebral cortex -- Periodicals; Brain -- Periodicals; 612.825
• DOI: 10.1093/cercor/bhac443
• Languages: English
• ISSNs: 1047-3211

Abstract

Abstract: People can seamlessly integrate a vast array of information from what they see and hear in the noisy and uncertain world. However, the neural underpinnings of audiovisual integration continue to be a topic of debate. Using strict inclusion criteria, we performed an activation likelihood estimation meta-analysis on 121 neuroimaging experiments with a total of 2, 092 participants. We found that audiovisual integration is linked with the coexistence of multiple integration sites, including early cortical, subcortical, and higher association areas. Although activity was consistently found within the superior temporal cortex, different portions of this cortical region were identified depending on the analytical contrast used, complexity of the stimuli, and modality within which attention was directed. The context-dependent neural activity related to audiovisual integration suggests a flexible rather than fixed neural pathway for audiovisual integration. Together, our findings highlight a flexible multiple pathways model for audiovisual integration, with superior temporal cortex as the central node in these neural assemblies.