Association between pre‐pregnancy body mass index and gestational weight gain and perinatal outcomes in pregnant women diagnosed with gestational diabetes mellitus: The Japan Environment and Children's Study. Issue 5 (22nd December 2021)

• Record Type: Journal Article
• Authors: Saito, Yoshihiro; Kobayashi, Sumitaka; Ikeda‐Araki, Atsuko; Ito, Sachiko; Miyashita, Chihiro; Kimura, Takashi; Hirata, Takumi; Tamakoshi, Akiko; Mayama, Michinori; Noshiro, Kiwamu; Nakagawa, Kinuko; Umazume, Takeshi; Chiba, Kentaro; Kawaguchi, Satoshi; Morikawa, Mamoru; Cho, Kazutoshi; Watari, Hidemichi; Ito, Yoshiya; Saijo, Yasuaki; Kishi, Reiko
• Other Names: Kamijima Michihiro investigator.; Yamazaki Shin investigator.; Ohya Yukihiro investigator.; Kishi Reiko investigator.; Yaegashi Nobuo investigator.; Hashimoto Koichi investigator.; Mori Chisato investigator.; Ito Shuichi investigator.; Yamagata Zentaro investigator.; Inadera Hidekuni investigator.; Nakayama Takeo investigator.; Iso Hiroyasu investigator.; Shima Masayuki investigator.; Kurozawa Youichi investigator.; Suganuma Narufumi investigator.; Kusuhara Koichi investigator.; Katoh Takahiko investigator.
• Is Part Of: Journal of diabetes investigation. Volume 13:Issue 5(2022)
• Page Start: 889
• Page End: 899
• Publication Date: 2021-12-22
• Subjects: Body mass index -- Gestational diabetes mellitus -- Gestational weight gain; Diabetes -- Periodicals; Diabetes -- Research -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462005
• DOI: 10.1111/jdi.13723
• Languages: English
• ISSNs: 2040-1116

Abstract

Abstract: Aims/Introduction: We investigated the association between gestational diabetes mellitus (GDM) and perinatal outcomes stratified by pre‐pregnancy body mass index (BMI) and/or gestational weight gain (GWG). Materials and Methods: Data from the national birth cohort in the Japan Environment and Children's Study from 2011 to 2014 ( n = 85, 228) were used. Japan uses the GDM guidelines of the International Association of Diabetes and Pregnancy Study Groups. The odds ratios (ORs) of perinatal outcomes were compared between women with and those without GDM. Results: The OR (95% confidence interval) of having a small for gestational age infant in the GDM group with a pre‐pregnancy BMI of ≥25.0 kg/m 2 and insufficient GWG (<2.75 kg) was 1.78 (1.02–3.12). The OR of having a large for gestational age infant of the same BMI group with excessive GWG (>7.25 kg) was 2.04 (1.56–2.67). The OR of hypertensive disorders of pregnancy was higher in women with a BMI ≥18.5 kg/m 2 in the GDM group than in the non‐GDM group. Conclusions: Large for gestational age and hypertensive disorders of pregnancy were associated with pre‐pregnancy BMI and GWG in either normal weight or overweight/obese women, and the relationship was strengthened when GDM was present. Women with GDM and a BMI of ≥25.0 kg/m 2 are at risk of having small for gestational age and large for gestational age infants depending on GWG. Abstract : We examined maternal characteristics and perinatal outcomes of women with gestational diabetes mellitus categorized by pre‐pregnant body mass index and gestational weight gain for the 85, 228 participants of a national birth cohort, the Japan Environment and Children's Study, collected from 2011 to 2014. Women with gestational diabetes mellitus and a body mass index of ≥25.0 kg/m 2 are at risk of having small for gestational age and LGA infants depending on gestational weight gain.