Tetralactam macrocycle based indicator displacement assay for colorimetric and fluorometric dual-mode detection of urinary uric acid. Issue 36 (17th April 2023)

• Record Type: Journal Article
• Authors: Yao, Huan; Li, Shi-Yao; Zhang, Hong; Pang, Xin-Yu; Lu, Jia-Le; Chen, Cong; Jiang, Wei; Yang, Liu-Pan; Wang, Li-Li
• Is Part Of: Chemical communications. Volume 59:Issue 36(2023)
• Page Start: 5411
• Page End: 5414
• Publication Date: 2023-04-17
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc06622j
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : An indicator displacement assay for colorimetric/fluorometric dual-mode detection of urinary uric acid was constructed using a naphthalene-based tetralactam macrocycle and phenoxazine dye, resorufin, which realized the visual detection of uric acid levels of volunteers. Abstract : An indicator displacement assay for colorimetric and fluorometric dual-mode detection of urinary uric acid (UA) was constructed using a water-soluble naphthalene-based tetralactam macrocycle and the phenoxazine dye, resorufin (RF ). The visual detection of UA levels of volunteers was successfully realized using modified paper assays, which could be used for the home monitoring of urinary UA.