Cervical Steroid Injections Are Not Effective for Prevention of Surgical Treatment of Degenerative Cervical Myelopathy. Issue 5 (June 2023)

• Record Type: Journal Article
• Authors: Manzur, Mustfa K.; Samuel, Andre M.; Vaishnav, Avani; Gang, Catherine Himo; Sheha, Evan D.; Qureshi, Sheeraz A.
• Is Part Of: Global spine journal. Volume 13:Issue 5(2023)
• Page Start: 1237
• Page End: 1242
• Publication Date: 2023-06
• Subjects: cervical spine -- steroid injections -- degenerative cervical myelopathy -- degenerative disc disease -- spinal cord compression -- epidural injection -- transforaminal injection -- zygapophyseal injection -- spinal fusion -- insurance database; Spine -- Diseases -- Periodicals; Spine -- Diseases -- Treatment -- Periodicals; Spine -- Abnormalities -- Periodicals; Spine -- Surgery -- Periodicals; 616.73
• DOI: 10.1177/21925682211024573
• Languages: English
• ISSNs: 2192-5682

Abstract

Study Design: Retrospective cohort study. Objective: The objective of this study is to determine how often patients with degenerative cervical myelopathy (DCM) and initially treated with cervical steroid injections (CSI) and to determine whether these injections provide any benefit in delaying ultimate surgical treatment. Methods: All patients with a new diagnosis of DCM, without previous cervical spine surgery or steroid injections, were identified in PearlDiver, a large insurance database. Steroid injection and surgery timing was identified using Current Procedural Terminology (CPT) codes. Multivariate logistic regression identified associations with surgical treatment. Results: A total of 686 patients with DCM were identified. Pre-surgical cervical spine steroid injections were utilized in 244 patients (35.6%). All patients underwent eventual surgical treatment. Median time from initial DCM diagnosis to surgery was 75.5 days (mean 351.6 days; standard deviation 544.9 days). Cervical steroid injections were associated with higher odds of surgery within 1 year (compared to patients without injections, OR = 1.44, P < .001) and at each examined time point through 5 years (OR = 2.01, P < .001). In multivariate analysis comparing injection types, none of the 3 injection types were associated with decreased odds of surgery within 1 month of diagnosis. Conclusions: While cervical steroid injections continue to be commonly performed in patients with DCM, there is an overall increased odds of surgery after any type of cervical injection. Therefore injections should not be used to prevent surgical management of DCM.