Design, fabrication, in vivo and in vitro characterizations of novel PLGA thread-embedding materials for juvenile pseudo-myopia. Issue 2 (1st February 2021)

• Record Type: Journal Article
• Authors: Fu, Shaoju; Zhang, Peihua
• Is Part Of: Journal of the Textile Institute. Volume 112:Issue 2(2021)
• Page Start: 216
• Page End: 222
• Publication Date: 2021-02-01
• Subjects: Polylactic-co-glycolic acid (PLGA) -- acupoint catgut-embedding (ACE) -- cell viability -- histological evaluation; Textile industry -- Periodicals; Textile fabrics -- Periodicals; Periodicals; 677.005
• DOI: 10.1080/00405000.2020.1732183
• Languages: English
• ISSNs: 0040-5000

Abstract

Abstract: Polylactic-co-glycolic acid (PLGA) acupoint catgut-embedding (ACE) multifilament was braided into thread structure, in vivo and in vivo performances were fully investigated. These findings indicated that samples had the relatively intact structures in the first 4 weeks, and their weights lost more than 80% in the 10 weeks. With the further degradation, mechanical properties became worse, a sharp decrease was observed in the 6 weeks. Samples presented more than 75% of cells being viable, and the surrounding tissues of samples grew well according to Hematoxylin and eosin (H&E) staining measurement. In sum, these findings warrant further study on PLGA embedding materials with outstanding clinical efficacy.