Mechanisms of recurrent laryngeal nerve injury in endoscopic thyroidectomy for papillary thyroid carcinoma: A large data from China. Issue 2 (20th March 2023)

• Record Type: Journal Article
• Authors: Xu, Wei; Teng, Changsheng; Ding, Guoqian; Zhao, Ning
• Is Part Of: Laryngoscope investigative otolaryngology. Volume 8:Issue 2(2023)
• Page Start: 604
• Page End: 609
• Publication Date: 2023-03-20
• Subjects: endoscopic thyroidectomy -- intraoperative nerve monitoring -- papillary thyroid carcinoma -- recurrent laryngeal nerve injury -- surgery; Otolaryngology -- Periodicals; Laryngoscopy -- Periodicals; Otolaryngology; Otolaryngology; Periodicals; Periodicals; 617.51
• DOI: 10.1002/lio2.1043
• Languages: English
• ISSNs: 2378-8038

Abstract

Abstract: Purpose: To investigate the mechanisms of recurrent laryngeal nerve (RLN) injury during endoscopic thyroidectomy via breast approach (ET‐BA) in patients with papillary thyroid carcinoma (PTC). Methods: The records of 416 PTC patients who underwent ET‐BA with intraoperative neural monitoring (IONM) from May 2015 to May 2021 in Beijing Friendship Hospital affiliated to Capital Medical University were retrospectively analyzed. Results: All patients were women. Mean age was 37.80 (7.87) years. The ET‐BA was performed in 416 patients. Overall incidence of RLN injury was 4.3% (18 patients). Injury was transient in 13 patients (3.1%) and permanent in five (1.2%). Macroscopic physical changes were apparent in the injured nerve in five patients (27.8%) and postoperative hoarseness or cough after drinking water were present in 11 (61.1%). Two RLN injuries occurred during nerve identification at the RLN laryngeal entry point into the surgical field, 15 during early nerve dissection somewhere between the first 0.5 and 2 cm of the nerve's course through the surgical field, and one occurred distal to 2 cm. The percentage of patients with separation, transection, traction and thermal mechanisms of injury was 27.8%, 22.2%, 22.2%, and 16.7%, respectively. The mechanism of injury was unknown in 11.1%. Conclusions: RLN injury may still occur during ET‐BA despite endoscopic magnification and early nerve identification even when IONM is used. Separation, transection, and traction injuries were the most frequent causes of injury. Abstract : The present study is a large, monocentric, retrospective analysis on a cohort of consecutive papillary thyroid carcinoma (PTC) patients submitted to an endoscopic thyroidectomy (ET) from May 2015 and May 2021. The records of 416 PTC patients who underwent ET with intraoperative neural monitoring (IONM) in Beijing Friendship Hospital affiliated to Capital Medical University were retrospectively analyzed. We concluded that RLN injury may still occur during endoscopic thyroidectomy via breast approach (ET‐BA) despite endoscopic magnification and early nerve identification even when IONM is used. Separation, transection, and traction injuries were the most frequent causes of injury.