Ceria Nanoparticles as Copper Chaperones that Activate SOD1 for Synergistic Antioxidant Therapy to Treat Ischemic Vascular Diseases (Adv. Mater. 16/2023). Issue 16 (20th April 2023)

• Record Type: Journal Article
• Authors: Im, Gwang‐Bum; Kim, Young Geon; Yoo, Tae Yong; Kim, Yeong Hwan; Kim, Kang; Hyun, Jiyu; Soh, Min; Hyeon, Taeghwan; Bhang, Suk Ho
• Is Part Of: Advanced materials. Volume 35:Issue 16(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-04-20
• Subjects: anti‐inflammation -- antioxidants -- nanozymes -- oxidative stress -- superoxide dismutase 1; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.202370114
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : Therapeutic Antioxidants In article number 2208989, Gwang‐Bum Im, Young Geon Kim, Tae Yong Yoo, Taeghwan Hyeon, Suk Ho Bhang, and co‐workers report the therapeutic effect of copper‐deposited ceria nanoparticles (CuCe NPs) on ischemic vascular diseases. They exhibit enhanced antioxidant effects over pristine ceria nanoparticles as the released copper buffers the depletion of glutathione while providing the bioavailable copper as a cofactor for the antioxidant enzyme, superoxide dismutase 1.