Biologicals in IgE-mediated food allergy. Issue 3 (28th June 2023)

• Record Type: Journal Article
• Authors: Mutarelli, Antonio; Giavina-Bianchi, Bruna; Arasi, Stefania; Cafarotti, Arianna; Fiocchi, Alessandro
• Is Part Of: Current opinion in allergy and clinical immunology. Volume 23:Issue 3(2023)
• Page Start: 205
• Page End: 209
• Publication Date: 2023-06-28
• Subjects: anaphylaxis -- antibodies -- food hypersensitivity -- humanized -- monoclonal -- omalizumab -- quality of life; Allergy -- Periodicals; Clinical immunology -- Periodicals; Hypersensitivity; Immunity; Immune System Diseases; Allergy and Immunology; 616.079
• DOI: 10.1097/ACI.0000000000000900
• Languages: English
• ISSNs: 1528-4050

Abstract

Abstract : Purpose of review: A better understanding of the most recent scientific literature in the use of biological therapy in the treatment of patients with IgE-mediated food allergy. Recent findings: A systematic review and meta-analysis demonstrated safety and effectiveness of omalizumab in the treatment of food allergy. The findings support the potential use of omalizumab as a monotherapy or as an adjunct to oral immunotherapy in IgE-mediated cow's milk allergy. The potential use of other biologics in the management of food allergy is subject of speculation. Summary: Different biological therapies are under evaluation for food allergic patients. The advance in literature will guide for a personalized treatment in the near future. However, additional research is needed to better understand the best candidate for each treatment, the optimal dose and timing.