BACILLARY LAYER DETACHMENT IN A KOREAN COHORT WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION. Issue 6 (June 2022)

• Record Type: Journal Article
• Authors: Kim, Jae Hui; Kim, Jong Woo; Kim, Chul Gu
• Is Part Of: Retina. Volume 42:Issue 6(2022)
• Page Start: 1028
• Page End: 1037
• Publication Date: 2022-06
• Subjects: age-related macular degeneration -- bacillary layer detachment -- choroidal neovascularization -- polypoidal choroidal vasculopathy -- subretinal hemorrhage; Retina -- Diseases -- Periodicals; Retinal Diseases; Vitreous Body; 617.735
• DOI: 10.1097/IAE.0000000000003437
• Languages: English
• ISSNs: 0275-004X

Abstract

Abstract : Bacillary layer detachment was observed in 4.5% of the macular neovascularization, with the highest incidence in Type 2 macular neovascularization. Eyes with bacillary layer detachment had greater macular thickness and poorer visual acuity than those without it. Abstract : Purpose: To evaluate the incidence and characteristics of bacillary layer detachment (BALAD) in neovascular age-related macular degeneration. Methods: This retrospective study was performed at Kim's Eye Hospital in South Korea. Patients who were diagnosed with neovascular age-related macular degeneration between January 2017 and December 2017 were included. The incidence of BALAD was compared among different types of macular neovascularization (MNV). The best-corrected visual acuity and central retinal thickness at diagnosis were compared between patients showing BALAD at diagnosis and those who did not. Results: Among the 442 patients included, BALAD was observed in 20 patients (4.5%). There was a significant difference in the incidence of BALAD between Type 1 MNV (2.7%), Type 2 MNV (12.5%), and Type 3 MNV (0%) ( P < 0.001). The best-corrected visual acuity was significantly worse (mean 1.26 ± 0.79 vs. 0.62 ± 0.50, P = 0.001), and the central retinal thickness was significantly greater (mean 648.2 ± 211.1 µ m vs. 464.0 ± 175.5 µ m, P < 0.001) in patients with BALAD than in those without it. After antivascular endothelial growth factor therapy, all BALADs resolved. Conclusion: This study first reported the incidence of the BALAD in neovascular age-related macular degeneration in a Korean population. The incidence of BALAD was the highest in Type 2 MNVs. Bacillary layer detachment generally develops in eyes with great macular thickness and poor visual acuity.