Exercise capacity following ventricular assist device implantation via thoracotomy with outflow cannula anastomosis to the descending aorta. Issue 11 (5th July 2021)

• Record Type: Journal Article
• Authors: Dorken Gallastegi, Ander; Kahraman, Ümit; Yağmur, Burcu; Çınar, Ece; Nalbantgil, Sanem; Engin, Çağatay; Yağdı, Tahir; Özbaran, Mustafa
• Is Part Of: Artificial organs. Volume 45:Issue 11(2021)
• Page Start: 1317
• Page End: 1327
• Publication Date: 2021-07-05
• Subjects: 6‐minute walk test -- cardiopulmonary exercise test -- congestive heart failure -- exercise capacity -- heart failure -- left ventricular assist device -- mechanical circulatory support -- oxygen consumption at peak exercise -- vO2max; Artificial organs -- Periodicals; 617.956
• DOI: 10.1111/aor.14021
• Languages: English
• ISSNs: 0160-564X

Abstract

Abstract: Left ventricular assist device (LVAD) implantation via left lateral thoracotomy with outflow cannula anastomosis to the descending aorta is an alternative technique that avoids anterior mediastinal planes and requires a single incision. This study compares changes in exercise capacity following LVAD implantation with outflow cannula anastomosis to the descending aorta versus ascending aorta. Adult patients who received a continuous flow centrifugal LVAD implantation and completed both pre‐ and postimplantation cardiopulmonary exercise tests (CPETs) and or 6‐minute walk tests (6MWT) were included. Change in CPET parameters (maximum oxygen intake: vO2 max, oxygen uptake efficiency ratio: OUES, ventilatory efficiency ratio: vE/vCO2 Slope) and 6MWT distance were compared between ascending and descending aorta anastomosis groups. Ascending and descending aorta anastomosis cohorts included 59 and 14 patients, respectively. Pre‐ and postimplantation CPETs were performed 63 ± 12 days before and 216 ± 17 days following implantation. The improvement in CPET parameters (vO2 max, OUES, vE/vCO2 Slope) or 6MWT distance was not significantly different between the ascending and descending aorta anastomosis groups. This study found no significant difference in the improvement of CPET parameters or 6MWT distance between LVAD implantation via thoracotomy with outflow cannula anastomosis to descending aorta and standard implantation via sternotomy with outflow cannula anastomosis to ascending aorta. Abstract : Retrospective evaluation of the improvement in cardiopulmonary exercise test parameters following left ventricular assist device (LVAD) implantation via left lateral thoracotomy with outflow cannula anastomosis to the descending aorta. There was no difference in the improvement of cardiopulmonary exercise test parameters (vO2 max, OUES and VE/vCO2 ) or 6‐minute walk distance between LVAD implantation via thoracotomy with outflow cannula anastomosis to the descending aorta and standard implantation (sternotomy with outflow cannula anastomosis to the ascending aorta).