Cerebrospinal fluid flow on time‐spatial labeling inversion pulse images before and after treatment of congenital hydrocephalus in a dog. (9th January 2021)

• Record Type: Journal Article
• Authors: Ito, Daisuke; Ishikawa, Chieko; Jeffery, Nick D.; Kitagawa, Masato
• Is Part Of: Journal of veterinary internal medicine. Volume 35:Number 1(2021)
• Page Start: 490
• Page End: 496
• Publication Date: 2021-01-09
• Subjects: CSF -- hydromyelia -- magnetic resonance imaging -- syringomyelia -- Time‐SLIP; Veterinary medicine -- Periodicals; 636.0896
• DOI: 10.1111/jvim.16020
• Languages: English
• ISSNs: 0891-6640

Abstract

Abstract: A 3‐month‐old male cross‐breed dog presented with signs of progressive diffuse brain disease. Noncommunicating congenital hydrocephalus concurrent with cervical syringomyelia was diagnosed on magnetic resonance images. On time‐spatial labeling inversion pulse (Time‐SLIP) images CSF flow through the mesencephalic aqueduct was poorly defined and there was flow into the syrinx across the craniocervical junction. After percutaneous ventricular drainage and ventriculoperitoneal shunting, CSF flow through the aqueduct was clearly detected and flow into the syrinx disappeared. In addition, CSF flow in the subarachnoid space at the pons and ventral aspect of the cervical subarachnoid space was restored. Signs of neurological dysfunction improved after ventriculoperitoneal shunting and the cerebral parenchyma was increased in thickness on 2‐year follow‐up computed tomography images. Patterns of CSF flow on Time‐SLIP images before and after CSF drainage or ventriculoperitoneal shunting aid in clarifying disease pathogenesis and confirm effects of CSF drainage.