Cover Feature: Regulating Antifreeze Activity through Water: Latent Functions of the Sugars of Antifreeze Glycoprotein Revealed by Total Chemical Synthesis (Chem. Eur. J. 21/2023). Issue 21 (9th March 2023)

• Record Type: Journal Article
• Authors: Okamoto, Ryo; Orii, Ryo; Shibata, Hiroyuki; Maki, Yuta; Tsuda, Sakae; Kajihara, Yasuhiro
• Is Part Of: Chemistry. Volume 29:Issue 21(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-03-09
• Subjects: antifreeze -- glycoproteins -- hydration -- total chemical synthesis; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.202300690
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : The sugar moiety of the antifreeze glycoprotein AFGP can form a unique dynamic water phase that includes disordered water molecules thereby inhibiting the freezing process. The property of this water phase seems to depend on both the structure and the number of sugar moieties. More information can be found in the Research Article by R. Okamoto, Y. Kajihara, and co‐workers (DOI: 10.1002/chem.202203553 ).