Voltammetric Determination of Favipiravir Used as an Antiviral Drug for the Treatment of Covid‐19 at Pencil Graphite Electrode. Issue 4 (16th November 2022)

• Record Type: Journal Article
• Authors: Erşan, Teslime; Dilgin, Didem Giray; Kumrulu, Elif; Kumrulu, Umur; Dilgin, Yusuf
• Is Part Of: Electroanalysis. Volume 35:Issue 4(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-11-16
• Subjects: COVID-19 -- Favipiravir -- Pencil graphite electrode -- Differential Pulse Voltammetry; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.202200295
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: This work describes the sensitive voltammetric determination of favipiravir (FAV) based on its reduction for the first time with a low‐cost and disposable pencil graphite electrode (PGE). In addition, the determination of FAV was also performed based on its oxidation. Differential pulse (DP) voltammograms recorded in 0.5 M H2 SO4 for the reduction of FAV show that peak currents increase linearly in the range of 1.0 to 600.0 μM with a limit of detection of 0.35 μM. The acceptable recovery values (98.9–106.0 %) obtained from a pharmaceutical tablet, real human urine, and artificial blood serum samples spiked with FAV confirm the high accuracy of the proposed method. Abstract :