WEE1 Dependency and Pejorative Prognostic Value in Triple‐Negative Breast Cancer. Issue 17 (6th July 2021)
- Record Type:
- Journal Article
- Title:
- WEE1 Dependency and Pejorative Prognostic Value in Triple‐Negative Breast Cancer. Issue 17 (6th July 2021)
- Main Title:
- WEE1 Dependency and Pejorative Prognostic Value in Triple‐Negative Breast Cancer
- Authors:
- de Nonneville, Alexandre
Finetti, Pascal
Birnbaum, Daniel
Mamessier, Emilie
Bertucci, François - Abstract:
- Abstract : The WEE1 G2 checkpoint kinase acts as a negative cell cycle regulator for entry into mitosis (G2‐to‐M transition). This comment extends a recent Advanced Science paper by reporting higher WEE1‐dependency of triple negative breast cancer (TNBC) cell lines, pejorative prognostic value of WEE1 expression in TNBC clinical samples as well as higher expression of biomarkers of sensitivity to WEE1 inhibitor.
- Is Part Of:
- Advanced science. Volume 8:Issue 17(2021)
- Journal:
- Advanced science
- Issue:
- Volume 8:Issue 17(2021)
- Issue Display:
- Volume 8, Issue 17 (2021)
- Year:
- 2021
- Volume:
- 8
- Issue:
- 17
- Issue Sort Value:
- 2021-0008-0017-0000
- Page Start:
- n/a
- Page End:
- n/a
- Publication Date:
- 2021-07-06
- Subjects:
- cell cycle -- expression -- survival -- triple‐negative breast cancer -- WEE1
Science -- Periodicals
505 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2198-3844 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/advs.202101030 ↗
- Languages:
- English
- ISSNs:
- 2198-3844
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 26945.xml