A position- and time-dependent pressure profile to model viscoelastic mechanical behavior of the brain tissue due to tumor growth. Issue 6 (26th April 2023)

• Record Type: Journal Article
• Authors: Abdolkarimzadeh, Fatemeh; Ashory, Mohammad Reza; Ghasemi-Ghalebahman, Ahmad; Karimi, Alireza
• Is Part Of: Computer methods in biomechanics and biomedical engineering. Volume 26:Issue 6(2023)
• Page Start: 660
• Page End: 672
• Publication Date: 2023-04-26
• Subjects: Brain tumor -- viscoelastic -- inverse finite element -- optimization -- pressure boundary; Biomechanics -- Data processing -- Periodicals; Biomedical engineering -- Periodicals; Biomechanics -- Periodicals; Biomedical Engineering -- methods -- Periodicals; Computing Methodologies -- Periodicals; 612.7
• DOI: 10.1080/10255842.2022.2082245
• Languages: English
• ISSNs: 1025-5842

Abstract

Abstract: This study proposed a computational framework to calculate the resultant position- and time-dependent pressure profile on the brain tissue due to tumor growth. A finite element (FE) patch of the brain tissue was constructed and an inverse dynamic FE-optimization algorithm was used to calculate its viscoelastic mechanical properties under compressive uniaxial loading. Two patient-specific post-tumor resection FE models were input to the FE-optimization algorithm to calculate the optimized 3 rd -order position-dependent and normal distribution time-dependent pressure profile parameters. The optimized viscoelastic material properties, the most suitable simulation time, and the optimized 3 rd -order position- and -time-dependent pressure profiles were calculated.