Cellular Bone Matrix Leading to Disseminated Tuberculosis After Spinal Fusion: A Report of 2 Cases. Issue 2 (24th April 2023)

• Record Type: Journal Article
• Authors: Issa, Tariq Z.; Lambrechts, Mark J.; Toci, Gregory R.; D'Antonio, Nicholas D.; Kanhere, Arun P.; Lingenfelter, Kenneth; Schroeder, Gregory D.; Vaccaro, Alexander R.
• Is Part Of: JBJS case connector. Volume 13:Issue 2(2023)
• Publication Date: 2023-04-24
• Subjects: lumbar fusion -- cervical fusion -- irrigation and debridement -- mycobacterium -- osteomyelitis -- infection -- tuberculosis -- cellular bone matrix; Orthopedic surgery -- Case studies -- Periodicals; Orthopedic surgery -- Periodicals; Orthopedics; Orthopedic Procedures; Orthopedic surgery; Periodicals; Electronic journals; Case studies; Periodicals; 616.7
• DOI: 10.2106/JBJS.CC.23.00047
• Languages: English
• ISSNs: 2160-3251

Abstract

Abstract : Case: Although implanted tuberculosis (TB) is rare, a single lot of cellular bone matrix was found to be infected with TB, leading to devastating outcomes. We present 2 cases referred to our institution because of instrumentation failure caused by TB inoculation of cellular bone matrix. Conclusion: Irrespective of spinal region of implanted TB infection, excision of infected bone, extensive irrigation and debridement, and instrumented stabilization are of primary importance to ensure TB eradication and adequate stabilization.