Acidity‐Biodegradable Iridium‐Coordinated Nanosheets for Amplified Ferroptotic Cell Death Through Multiple Regulatory Pathways (Adv. Healthcare Mater. 10/2023). Issue 10 (17th April 2023)

• Record Type: Journal Article
• Authors: Huang, Lili; Nie, Tongtong; Jiang, Lixian; Chen, Ying; Zhou, Yixuan; Cai, Xiaojun; Zheng, Yuanyi; Wang, Longchen; Wu, Jianrong; Ying, Tao
• Is Part Of: Advanced healthcare materials. Volume 12:Issue 10(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-04-17
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.202370050
• Languages: English
• ISSNs: 2192-2640

Abstract

Abstract : Ferroptosis In article 2202562 by Longchen Wang, Jianrong Wu, Tao Ying, and co‐workers, an aciditybiodegradable Ir‐Hemin nanosheet is presented to achieve notable ferroptosis efficacy through multiple regulatory pathways, including SDT‐triggered ROS generation, GPX4 inhibition and HO‐1 upregulation‐mediated endogenous Fe 2+ elevation. This work paves a new way for future studies exploring nanomaterials as ferroptosis inducers.