Front Cover: Strapped Porphyrins as Model Systems for Atropisomeric Photosensitizer Drugs (Eur. J. Org. Chem. 15/2023). Issue 15 (5th April 2023)

• Record Type: Journal Article
• Authors: Donohoe, Claire; Charisiadis, Asterios; Maguire, Sophie; Twamley, Brendan; Schaberle, Fábio A.; Gomes‐da‐Silva, Lígia C.; Senge, Mathias O.
• Is Part Of: European journal of organic chemistry. Volume 26:Issue 15(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-04-05
• Subjects: atropisomerism -- drug design -- photodynamic therapy -- porphyrins -- photochemistry; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202300270
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : The Front Cover illustrates how molecular shape can control drug uptake. Using strapped porphyrins as models for atropisomeric drugs, the artwork shows that molecules with polar groups on one side of the macrocycle can cross the cell membrane while those with other orientations do not. Cover design by Ella Marushchenko. More information can be found in the Research Article by L. C. Gomes‐da‐Silva, M. O. Senge et al .