Stage M Infantile Neuroblastoma With Involvement of Falx Cerebri: Case Report and Literature Review. Issue 4 (19th May 2023)

• Record Type: Journal Article
• Authors: Sai, Miyu; Moriya, Kunihiko; Kaino, Akira; Suzuki, Tasuku; Katayama, Saori; Aoki, Hidekazu; Sasahara, Yoji
• Is Part Of: Journal of pediatric hematology/oncology. Volume 45:Issue 4(2023)
• Page Start: 220
• Page End: 222
• Publication Date: 2023-05-19
• Subjects: infantile neuroblastoma -- falx cerebri -- stage M -- multiple metastasis -- minimized chemotherapy; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000002548
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Neuroblastoma is the most common extracranial solid tumor in children. When metastasis to the falx cerebri is present, it is classified as stage M; however, its behavior has not been well characterized. Here we present a case of stage M infantile neuroblastoma (NB) with involvement of the falx cerebri, and also summarize the clinical profiles of previously reported cases. Notably, all of the tumors resolved with low-dose chemotherapy alone. Although further study is needed to distinguish NBs presenting at these different intracranial locations, NB with metastasis to the falx cerebri may be categorized as MS when diagnosed at less than 18 months of age.