Psychiatric comorbidities of obsessive‐compulsive disorder: A series of systematic reviews and meta‐analyses. Issue 4 (6th September 2021)

• Record Type: Journal Article
• Authors: Rowe, Charlotte; Deledalle, Aurore; Boudoukha, Abdel Halim
• Is Part Of: Journal of clinical psychology. Volume 78:Issue 4(2022)
• Page Start: 469
• Page End: 484
• Publication Date: 2021-09-06
• Subjects: meta‐analysis -- obsessive‐compulsive disorder -- psychiatric comorbidities -- systematic review; Psychology -- Periodicals; 616.89
• DOI: 10.1002/jclp.23240
• Languages: English
• ISSNs: 0021-9762

Abstract

Abstract: Objective: Although there is a growing number of studies on psychiatric comorbidities of obsessive‐compulsive disorder (OCD), controversy remains about the strength of associations between some disorders. We present a series of systematic reviews and meta‐analyses examining four psychiatric disorders frequently associated with OCD—depression, bipolar disorder, substance abuse disorder and psychosis. Methods: Three electronic databases were searched up to May 2017; PsycINFO, Medline, and Web of Science. Meta‐analyses using random effects models were conducted. Results: The meta‐analyses found strong associations between all comorbidities and OCD, particularly for depression. In addition, a series of systematic reviews were conducted giving information about the characteristics of these psychiatric associations. Conclusion: It is probable that these disorders share common etiological factors, and thus trans‐diagnostic processes must be addressed when offering treatment. Clinical implications of these findings are discussed with suggestions for further research in the area.