Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine. Issue 2 (12th April 2022)

• Record Type: Journal Article
• Authors: Hongzhi, Du; Xiaoying, Hou; Yujie, Guo; Le, Chen; Yuhuan, Miao; Dahui, Liu; Luqi, Huang
• Is Part Of: Animal models and experimental medicine. Volume 5:Issue 2(2022)
• Page Start: 108
• Page End: 119
• Publication Date: 2022-04-12
• Subjects: anti‐inflammatory effect -- inflammation and related diseases -- the classical mechanisms -- the experimental models -- traditional Chinese medicine; Laboratory animals -- Periodicals; Diseases -- Animal models -- Periodicals; Animal models in research -- Periodicals; Veterinary medicine -- Periodicals; Laboratory Animal Science; Disease Models, Animal; Animals, Laboratory; Animal Welfare; Veterinary Medicine; Animal models in research; Diseases -- Animal models; Laboratory animals; Veterinary medicine; Periodicals; Fulltext; Internet Resources; Periodicals; Periodicals; 616.0273
• DOI: 10.1002/ame2.12224
• Languages: English
• ISSNs: 2576-2095

Abstract

Abstract: Inflammation is a common disease involved in the pathogenesis, complications, and sequelae of a large number of related diseases, and therefore considerable research has been directed toward developing anti‐inflammatory drugs for the prevention and treatment of these diseases. Traditional Chinese medicine (TCM) has been used to treat inflammatory and related diseases since ancient times. According to the review of abundant modern scientific researches, it is suggested that TCM exhibit anti‐inflammatory effects at different levels, and via multiple pathways with various targets, and recently a series of in vitro and in vivo anti‐inflammatory models have been developed for anti‐inflammation research in TCM. Currently, the reported classic mechanisms of TCM and experimental models of its anti‐inflammatory effects provide reference points and guidance for further research and development of TCM. Importantly, the research clearly confirms that TCM is now and will continue to be an effective form of treatment for many types of inflammation and inflammation‐related diseases. Abstract : Inflammatory is a common disease and involved in the pathogenesis, complications, as well as sequelae of a large number of related diseases. Therefore, people have been devoted to develop anti‐inflammatory drugs for the prevention and treatment of diseases. In fact, Traditional Chinese medicine (TCM) has been used to treat inflammatory and related diseases since ancient times. According to the review of abundant modern scientific researches, it is suggested that TCM exhibit anti‐inflammatory effect via different levels, multiple pathways and various targets. And a series of in vitro and in vivo anti‐inflammatory models have been developed for anti‐inflammatory research of TCM. Nowadays, these reported classical mechanisms and experimental models of anti‐inflammatory effect for TCM can provide reference and guidance for further research and development of TCM. Importantly, it is convinced that TCM is and will be an effective treatment for a variety of inflammation and inflammation‐related diseases.