Determination of molecular hydration in solution via changes in magnetic anisotropy. Issue 30 (28th March 2023)

• Record Type: Journal Article
• Authors: Giansiracusa, Marcus J.; Vonci, Michele; Whyatt, Yasmin L.; Williams, Carys; Mason, Kevin; Parker, David; McInnes, Eric J. L.; Chilton, Nicholas F.
• Is Part Of: Chemical communications. Volume 59:Issue 30(2023)
• Page Start: 4531
• Page End: 4534
• Publication Date: 2023-03-28
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d3cc00601h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. We use EPR to determine that a carboxylate PARASHIFT reagent coordinates water while the phosphinate analogue does not. Abstract : The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to unambiguously demonstrate that a t -butyl-pyridyl-functionalised Er III DOTA derivative coordinates water, while its methylphosphinate analogue does not.