Imidazole–carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging. Issue 30 (28th March 2023) - Pham, Thanh Chung
Abstract : A heavy-atom-free photosensitizer (CI ) showed strong singlet oxygen generation, efficient photodynamic therapy and fluorescence bioimaging under two-photon excitation. Abstract : A heavy-atom-free photosensitizer (CI ) based on an imidazole–carbazole conjugate exhibited strong fluorescence emission and ROS generation via both type I and II mechanisms. In particular, CI showed efficient photodynamic therapy and fluorescence bioimaging under two-photon (TP) excitation (740 nm) toward HeLa cells with negligible dark toxicity.