Enamel Based Composite Layers Deposited on Titanium Substrate with Antifungal Activity. (12th December 2016)

• Record Type: Journal Article
• Authors: Iconaru, S. L.; Prodan, A. M.; Turculet, C. S.; Beuran, M.; Ghita, R. V.; Costescu, A.; Groza, A.; Chifiriuc, M. C.; Chapon, P.; Gaiaschi, S.; Hristu, R.; Stanciu, G. A.; Trusca, R.; Ganciu, M.; Raita, S. M.; Vineticu, N.; Ciobanu, C. S.
• Other Names: Baker Mark Academic Editor.
• Is Part Of: Journal of spectroscopy. Volume 2016(2016)
• Publication Date: 2016-12-12
• Subjects: Spectrum analysis -- Periodicals; 543.505
• DOI: 10.1155/2016/4361051
• Languages: English
• ISSNs: 2314-4920

Abstract

Abstract : The goal of this paper was to investigate the antifungal activity of Enamel layers deposited on titanium substrate (Ti-Enamel) and Enamel layers deposited on titanium substrate previously coated with a vinyl polydimethylsiloxane layer (Ti-PDMS-Enamel). The physicochemical properties were also investigated. The Candida albicans biofilm development on the obtained layers was examined after 24 h, 48 h, and 72 h by confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM) after ethidium bromide staining. A significant inhibition of the fungal adherence and biofilm development was observed on Ti-Enamel layers. The antifungal results demonstrated that the use of new Ti-Enamel composite layers could represent a promising perspective for the prevention of fungal biofilms associated implant infections.