Development and Adsorption Characterization of Metal Affinity-Immobilized Magnetic Liposome. (11th February 2020)

• Record Type: Journal Article
• Authors: Lu, Yuan; Liao, Dankui; Feng, Xuezhen; Meng, Hualin; Lu, Yuting; Wei, Qiqiu; Duan, Siliang; Wu, Shanguang
• Other Names: Nishikiori Hiromasa Academic Editor.
• Is Part Of: Journal of nanomaterials. Volume 2020(2020)
• Publication Date: 2020-02-11
• Subjects: Nanostructured materials -- Periodicals; Nanotechnology -- Periodicals; Nanomatériaux; Nanostructured materials; Nanotechnology; Nanostructures; Nanotechnology; Periodicals; Fulltext; Internet Resources; Periodicals; 620.115
• DOI: 10.1155/2020/8731360
• Languages: English
• ISSNs: 1687-4110

Abstract

Abstract : A metal affinity-immobilized magnetic liposome (MA-IML) was prepared in this research, which was with lipid and Ni 2+ content of 143.25 μ g/mg and 32 μ mol/mg, respectively. The antihypertensive peptides Ile-Pro-Pro (IPP) and Val-Pro-Pro (VPP) could be adsorbed onto MA-IML under specific conditions, and the adsorption kinetics was explored. The pseudo-second-order kinetics (R 2 value > 0.98 ) was more suitable to describe the adsorption process of IPP and VPP than the intraparticle diffusion model and pseudo-first-order kinetic model. The results indicated that MA-IML could be used as an adsorbent for screening antihypertensive peptides from natural products.