Information–energy equivalence and the emergence of self-replicating biological systems. (April 2023)

• Record Type: Journal Article
• Authors: Paradis, Emmanuel
• Is Part Of: Bio systems. Volume 226(2023)
• Publication Date: 2023-04
• Subjects: Energy -- Entropy -- Genome -- Information -- Replication; Biological systems -- Periodicals; Biology -- Periodicals; Biology -- Periodicals; Evolution -- Periodicals; Biologie -- Périodiques; Évolution -- Périodiques; 570
• DOI: 10.1016/j.biosystems.2023.104885
• Languages: English
• ISSNs: 0303-2647

Abstract

Abstract: Biological processes are characterized by a decrease in entropy in apparent violation of the second law of thermodynamics. Information stored in genomes help to solve this paradox when interpreted under the relationship between information and energy stated by Brillouin in the 1950's. However, the origins of living forms from inanimate matter which have no information storage device remains an open question. In this paper, a theoretical approach is developed on this issue. The replication of a simple entity with a binary genome is assumed to require an information-equivalent energy in addition to the standard activation energy. It is found that, in some conditions, a decrease in entropy can be accomplished together with a decrease in Gibbs free energy. An equation of the total energy for the replication of this entity is derived. Three factors are predicted to lower this energy: a small number of states of the coding sequence, a lower temperature, and a high ratio of the reaction on diffusion coefficients. These factors may have favoured the emergence of evolutionary demons—information storage devices that are able to decrease entropy. It is evaluated that some short, single-stranded RNA sequences made only of G and of C may conform to this model. The consequences of this model and its predictions on the origins of life on Earth and on other planets are discussed. Graphical abstract: Highlights: An equation of the total energy for simple genome replication is derived. Decreases in entropy and in Gibbs free energy can be accomplished together. Some factors may have favoured the emergence of self-replicating biological systems. Short RNA sequences made of G and C may conform to these predictions.